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dracunculiasis - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

dracunculiasis

MONDO:0016472

Also known as:DracunculosisDracunculus medinensis caused disease or disorderDracunculus medinensis disease or disorder

Overview

Dracunculiasis (Guinea worm disease) is a neglected tropical disease (NTD) characterized by a painful burning skin lesion from which the Dracunculus medinensis parasite emerges approximately 1 year after infection resulting from consumption of unsafe drinking water containing parasite-infected copepods (Cyclops spp., microcrustacea also called water fleas).

Clinical Presentation

Built from Human Phenotype Ontology (HPO) phenotype annotations and GeneReviews clinical descriptions. Features represent findings documented across known cases — not an exhaustive list of possible symptoms.

Features include very common findings: Skin rash, Pruritus, Subcutaneous nodule, and Diarrhea and others; and common findings: Joint inflammation (arthritis), Limitation of joint mobility, Immunologic hypersensitivity, and Cellulitis and others. 15 total HPO annotations.

Organ System	Phenotype Count	Example Features
Skin	5	Skin rash, Pruritus, Subcutaneous nodule

Diagnosis

Biomarker and diagnostic research for dracunculiasis has been reported in the published literature.

Prognosis

Phenotype severity distribution: 8 very common features, 5 common features.

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for dracunculiasis.

162 publications have been identified in PubMed for dracunculiasis. Research spans Review / Meta-Analysis (43%), Basic Science / Preclinical (20%), and Case Report / Case Series (15%).

Research Type	Count	% of Total
Research summaries	70	43%

Data assembled from 4 of 12 sources · Last updated Sep 18, 2026, 2:35 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:231

GARD

Genetic and Rare Diseases Info Center

GARD:6286

Questions for Your Care Team

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Kisho

dracunculiasis

Overview

Clinical Presentation

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Questions for Your Care Team

Questions for Your Care Team

Explore clinical features

Recent Publications

dracunculiasis

Overview

Clinical Presentation

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Explore clinical features

Recent Publications