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An autoimmune disorder, similar to systemic lupus erythematosus, that is caused by certain drugs.
Features include very common findings: Blood in the urine (hematuria), Petechiae, Pericardial effusion, and Pericarditis and others; and common findings: Fever and Serositis. 23 total HPO annotations.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Lab test results | 4 | Elevated creatine kinase (muscle enzyme) (elevated circulating creatine kinase concentration), Antinuclear antibody positivity, Elevated CRP (inflammation marker) (elevated circulating c-reactive protein concentration) |
Phenotype severity distribution: 20 very common features, 2 common features.
Estimated prevalence: Unknown (Unknown prevalence).
No clinical trials have been registered for drug-induced lupus erythematosus.
58 publications have been identified in PubMed for drug-induced lupus erythematosus. Research spans Case Report / Case Series (64%), Review / Meta-Analysis (16%), and Epidemiology / Natural History (9%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 37 | 64% |
Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 3:50 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Blood and immune system | 3 | Low platelet count (thrombocytopenia), Low red blood cell count (anemia), Autoimmune antibody positivity |
Heart and blood vessels | 2 | Pericardial effusion, Pericarditis |
Kidneys and urinary system | 1 | Blood in the urine (hematuria) |
Lungs and breathing | 1 | Dyspnea |
Bones and joints | 1 | Arthralgia |
Muscles | 1 | Myalgia |
Skin | 1 | Malar rash |
Metabolism | 1 | Fever |
Research summaries
9 |
16% |
Disease patterns and progression | 5 | 9% |
Laboratory research | 4 | 7% |
Clinical study results | 2 | 3% |
Other research | 1 | 2% |
Gachiniard E (2026). [PMID: 42191551](https://pubmed.ncbi.nlm.nih.gov/42191551/). *Therapie*. [Other]
Mendpara V (2026). [PMID: 41838253](https://pubmed.ncbi.nlm.nih.gov/41838253/). *Int J Cardiovasc Imaging*. [Epidemiology / Natural History]
Saliba F (2026). [PMID: 28722919](https://pubmed.ncbi.nlm.nih.gov/28722919/). *Unknown Journal*. [Review / Meta-Analysis]
Sudhakaran SC (2026). [PMID: 41832425](https://pubmed.ncbi.nlm.nih.gov/41832425/). *BMC Gastroenterol*. [Epidemiology / Natural History]
Nagra D (2026). [PMID: 41918754](https://pubmed.ncbi.nlm.nih.gov/41918754/). *Front Immunol*. [Review / Meta-Analysis]
Tjiu JW (2026). [PMID: 41596733](https://pubmed.ncbi.nlm.nih.gov/41596733/). *International journal of molecular sciences*. [Case Report / Case Series]
Choi K (2026). [PMID: 42005202](https://pubmed.ncbi.nlm.nih.gov/42005202/). *Cureus*. [Case Report / Case Series]
Stark M (2026). [PMID: 41666880](https://pubmed.ncbi.nlm.nih.gov/41666880/). *Clinical practice and cases in emergency medicine*. [Clinical Trial Publication]
Marchionni E (2025). [PMID: 40919101](https://pubmed.ncbi.nlm.nih.gov/40919101/). *JAAD case reports*. [Case Report / Case Series]
García-González M (2025). [PMID: 41449875](https://pubmed.ncbi.nlm.nih.gov/41449875/). *International journal of rheumatic diseases*. [Case Report / Case Series]