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Biomarker and diagnostic research for DYRK1A-related intellectual disability syndrome due to 21q22.13q22.2 microdeletion has been reported in the published literature.
Estimated prevalence: <1 in 1,000,000 (VERY_RARE).
No clinical trials have been registered for DYRK1A-related intellectual disability syndrome due to 21q22.13q22.2 microdeletion.
111 publications have been identified in PubMed for DYRK1A-related intellectual disability syndrome due to 21q22.13q22.2 microdeletion. Research spans Case Report / Case Series (26%), Review / Meta-Analysis (25%), and Basic Science / Preclinical (23%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 29 | 26% |
Data assembled from 3 of 12 sources · Last updated Sep 21, 2026, 4:54 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Common questions about DYRK1A-related intellectual disability syndrome due to 21q22.13q22.2 microdeletion
Research summaries |
28 |
25% |
Laboratory research | 26 | 23% |
Disease patterns and progression | 14 | 13% |
Testing and diagnosis research | 12 | 11% |
Other research | 1 | 1% |
New treatment approaches | 1 | 1% |
Liu X (2026). [PMID: 41621842](https://pubmed.ncbi.nlm.nih.gov/41621842/). *Zhonghua Yi Xue Yi Chuan Xue Za Zhi*. [Case Report / Case Series]
Dixon AJ (2026). [PMID: 41869856](https://pubmed.ncbi.nlm.nih.gov/41869856/). *Am J Physiol Renal Physiol*. [Basic Science / Preclinical]
Maines J (2026). [PMID: 32491634](https://pubmed.ncbi.nlm.nih.gov/32491634/). *Unknown Journal*. [Diagnostic / Biomarker]
van Oirsouw ASE (2026). [PMID: 41954311](https://pubmed.ncbi.nlm.nih.gov/41954311/). *Clin Genet*. [Epidemiology / Natural History]
Papageorgiou L (2026). [PMID: 41751632](https://pubmed.ncbi.nlm.nih.gov/41751632/). *Genes (Basel)*. [Review / Meta-Analysis]
Costa SD (2026). [PMID: 40566944](https://pubmed.ncbi.nlm.nih.gov/40566944/). *J Child Neurol*. [Case Report / Case Series]
Kikas T (2026). [PMID: 41338233](https://pubmed.ncbi.nlm.nih.gov/41338233/). *Hum Reprod*. [Case Report / Case Series]
Gąsiorowska J (2026). [PMID: 42023627](https://pubmed.ncbi.nlm.nih.gov/42023627/). *Pediatr Endocrinol Diabetes Metab*. [Review / Meta-Analysis]
Bishop BN (2026). [PMID: 30860719](https://pubmed.ncbi.nlm.nih.gov/30860719/). *Unknown Journal*. [Review / Meta-Analysis]
Covarelli J (2025). [PMID: 40724914](https://pubmed.ncbi.nlm.nih.gov/40724914/). *Int J Mol Sci*. [Review / Meta-Analysis]