Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy
A pigmentation disease characterized by reticulate hyper- and hypo-pigmentated macules in a generalized distribution.
Features include very common findings: Hypermelanotic macule, Hypopigmented skin patches, Spotty hypopigmentation, and Macule; and common findings: Hearing loss (hearing impairment), Cutaneous photosensitivity, Freckling, and Multiple cafe-au-lait spots. 9 total HPO annotations.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Skin | 2 | Cutaneous photosensitivity, Hypopigmented skin patches |
Phenotype severity distribution: 4 very common features, 4 common features.
No clinical trials have been registered for dyschromatosis universalis hereditaria.
10 publications have been identified in PubMed for dyschromatosis universalis hereditaria. Research spans Review / Meta-Analysis (40%), Case Report / Case Series (40%), and Basic Science / Preclinical (20%).
Research Type | Count | % of Total |
|---|---|---|
Research summaries | 4 | 40% |
Data assembled from 4 of 12 sources · Last updated Sep 20, 2026, 3:05 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Ears |
1 |
Hearing loss (hearing impairment) |
Growth and development | 1 | Short stature |
Age of onset: childhood.
Patient case studies
4 |
40% |
Laboratory research | 2 | 20% |
Okamura K (2026). [PMID: 41127964](https://pubmed.ncbi.nlm.nih.gov/41127964/). *J Dermatol*. [Review / Meta-Analysis]
Wang XL (2025). [PMID: 41283180](https://pubmed.ncbi.nlm.nih.gov/41283180/). *World J Clin Cases*. [Case Report / Case Series]
Bishnoi A (2025). [PMID: 40511878](https://pubmed.ncbi.nlm.nih.gov/40511878/). *Pigment Cell Melanoma Res*. [Review / Meta-Analysis]
Cui H (2025). [PMID: 41284354](https://pubmed.ncbi.nlm.nih.gov/41284354/). *Pigment Cell Melanoma Res*. [Basic Science / Preclinical]
Yuan L (2025). [PMID: 40584949](https://pubmed.ncbi.nlm.nih.gov/40584949/). *Skin Health Dis*. [Review / Meta-Analysis]
Elizabeth Rosales Martínez Z (2025). [PMID: 41078419](https://pubmed.ncbi.nlm.nih.gov/41078419/). *JAAD Case Rep*. [Case Report / Case Series]
Wang T (2025). [PMID: 40115815](https://pubmed.ncbi.nlm.nih.gov/40115815/). *Front Genet*. [Case Report / Case Series]
Mohapatra L (2024). [PMID: 39139099](https://pubmed.ncbi.nlm.nih.gov/39139099/). *Clin Exp Dermatol*. [Review / Meta-Analysis]
Baril SA (2024). [PMID: 39557842](https://pubmed.ncbi.nlm.nih.gov/39557842/). *Nat Commun*. [Basic Science / Preclinical]
Goswami PR (2024). [PMID: 39310073](https://pubmed.ncbi.nlm.nih.gov/39310073/). *Int J Appl Basic Med Res*. [Case Report / Case Series]