Ebola Hemorrhagic Fever — Clinical Trials

MONDO:00057379 active·2 recruitingLast updated: Mar 17, 2026, 5:26 AM

Trial Landscape

Ebola Hemorrhagic Fever has a growing clinical research program, driven by biological therapy and drug treatment.

Recruiting

Active Trials

By Approach

Biological Therapy8

Drug Treatment2

2 additional trials involve behavioral, dietary, diagnostic, or observational approaches.

By Phase

Phase 1

Phase 2

Phase 3

Phase 4

Sponsor Types

Academic/Other9

Trial Locations

Democratic Republic of the Congo2 trials

United States2 trials

Sierra Leone2 trials

Germany1 trial

Guinea1 trial

Liberia1 trial

Trials often recruit across multiple countries, so totals exceed the trial count.

9 Trials

Phase 3Recruiting

NCT06126822

Safety and Immunogenicity of Ervebo® and Zabdeno® Booster Vaccines Against Ebola Virus Following Previous Vaccination with the Zabdeno/Mvabea® or Ervebo® Vaccine Schedules in DRC

Sponsor:Institute of Tropical Medicine, Belgium

Democratic Republic of the CongoStarted: Feb 2025Est. completion: Oct 2026Updated: Mar 2025

Phase 4Recruiting

NCT05992480

REVIVE (Response to the Ebola Virus Vaccine)

Sponsor:Tulane University

Sierra LeoneStarted: Dec 2025Est. completion: May 2026Updated: Dec 2025

Phase 3Not Yet Recruiting

NCT06841614

EBOla Post-Exposure Prophylaxis

Sponsor:ANRS, Emerging Infectious Diseases

Democratic Republic of the CongoStarted: Sep 2026Est. completion: Aug 2028Updated: Jan 2026

Phase 3Not Yet Recruiting

NCT05959421

Immunity Induced by VSV-EBOV and Assessment of a Booster Dose in Individuals at Potential Occupational Risk for Exposure

Sponsor:Universitätsklinikum Hamburg-Eppendorf

GermanyStarted: Jun 2026Est. completion: Jun 2028Updated: Apr 2025

Phase 2Not Yet Recruiting

NCT05202288

Impact of Delay Between Administration of Inmazeb Administration and Vaccination by Ervebo on Vaccine Immune Response on Healthy Volunteers

Sponsor:ANRS, Emerging Infectious Diseases

Started: Jan 2027Est. completion: Aug 2027Updated: Jan 2026

Phase 1Not Yet Recruiting

NCT05909358

Solidarity/Tokomeza Ebola Trial

Sponsor:Makerere University

Started: Jul 2023Est. completion: Sep 2027Updated: Jun 2023

Last updated over 18 months ago

Phase 4Not Yet Recruiting

NCT06587503

Safety and Immunogenicity of rVSVΔG-ZEBOV-GP Vaccination When Dosed Concurrently With mRNA COVID-19 Vaccine Booster Doses

Sponsor:University of Birmingham

Started: Oct 2024Est. completion: May 2025Updated: Sep 2024

Last updated over 18 months ago

Phase 2Active, Not Recruiting

NCT06803342

A Trial to Evaluate Safety, Tolerability, and Immune Responses of an Investigational Monovalent Chimpanzee Adenoviral Vectored Sudan Ebolavirus Vaccine in Healthy Adults

Sponsor:Albert B. Sabin Vaccine Institute

United StatesStarted: Jun 2025Est. completion: Apr 2027Updated: Feb 2026

Phase 2Active, Not Recruiting

NCT06100913

Immunology of Ebola Vaccine

Sponsor:Emory University

United StatesStarted: Aug 2024Est. completion: Aug 2027Updated: Jan 2026

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Data sourced from ClinicalTrials.gov via Kisho's automated pipeline. Trials refreshed every 4 hours for monitored diseases.

Last sync: March 17, 2026 at 5:26 AM