Biomarker and diagnostic research for Ehlers-Danlos syndrome, classic type has been reported in the published literature.

Phenotype severity distribution: 7 very common features, 11 common features.

Estimated prevalence: 1-9 in 100,000 (Uncommon).

No clinical trials have been registered for Ehlers-Danlos syndrome, classic type.

21 publications have been identified in PubMed for Ehlers-Danlos syndrome, classic type. Research spans Basic Science / Preclinical (45%), Case Report / Case Series (20%), and Review / Meta-Analysis (10%).

Recent Publications

• Kumskova M (2026). [PMID: 41284637](https://pubmed.ncbi.nlm.nih.gov/41284637/). *Blood*. [Basic Science / Preclinical]

• Bucarey SA (2026). [PMID: 41683375](https://pubmed.ncbi.nlm.nih.gov/41683375/). *Molecules (Basel, Switzerland)*. [Case Report / Case Series]

• Tsujioka Y (2026). [PMID: 42094029](https://pubmed.ncbi.nlm.nih.gov/42094029/). *Mol Syndromol*. [Review / Meta-Analysis]

• Zhao J (2026). [PMID: 41917426](https://pubmed.ncbi.nlm.nih.gov/41917426/). *Sci Rep*. [Basic Science / Preclinical]

• Conconi R (2025). [PMID: 40554838](https://pubmed.ncbi.nlm.nih.gov/40554838/). *Ultramicroscopy*. [Basic Science / Preclinical]

• Rostami S (2025). [PMID: 40989941](https://pubmed.ncbi.nlm.nih.gov/40989941/). *Plastic and reconstructive surgery. Global open*. [Case Report / Case Series]

• Ritelli M (2025). [PMID: 39225014](https://pubmed.ncbi.nlm.nih.gov/39225014/). *American journal of medical genetics. Part A*. [Diagnostic / Biomarker]

• van Gurp JE (2025). [PMID: 39807789](https://pubmed.ncbi.nlm.nih.gov/39807789/). *Clinical and translational gastroenterology*. [Epidemiology / Natural History]

• Anand L (2025). [PMID: 41356277](https://pubmed.ncbi.nlm.nih.gov/41356277/). *Case reports in genetics*. [Basic Science / Preclinical]

• Booij L (2025). [PMID: 40879253](https://pubmed.ncbi.nlm.nih.gov/40879253/). *The International journal of eating disorders*. [Case Report / Case Series]