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A rare iatrogenic disease characterized by paradoxical nasal obstruction and symptoms including air hunger and suffocation-like breathing sensation, nasal dryness and crusting, burning pain or cold airflow sensation, impaired sleep and cognitive function and severe anxiety and depression, and typically occurs after surgical reduction or removal of nasal turbinates.
Biomarker and diagnostic research for empty nose syndrome has been reported in the published literature.
1 clinical trial registered. Interventions under study include medical devices. Pipeline includes 1 NA. Research is primarily sponsored by academic and government institutions.
55 publications have been identified in PubMed for empty nose syndrome. Research spans Review / Meta-Analysis (24%), Clinical Trial Publication (22%), and Epidemiology / Natural History (13%).
Research Type | Count | % of Total |
|---|---|---|
Research summaries | 13 | 24% |
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 1:45 AM UTC
Clinical study results |
12 |
22% |
Disease patterns and progression | 7 | 13% |
Patient case studies | 6 | 11% |
Laboratory research | 5 | 9% |
New treatment approaches | 5 | 9% |
Other research | 3 | 6% |
Testing and diagnosis research | 3 | 6% |
Galaverni G (2026). [PMID: 42027390](https://pubmed.ncbi.nlm.nih.gov/42027390/). *Front Bioeng Biotechnol*. [Review / Meta-Analysis]
Van Hollebeke M (2026). [PMID: 41319124](https://pubmed.ncbi.nlm.nih.gov/41319124/). *Curr Opin Crit Care*. [Review / Meta-Analysis]
Maniaci A (2026). [PMID: 41598728](https://pubmed.ncbi.nlm.nih.gov/41598728/). *J Clin Med*. [Diagnostic / Biomarker]
Hosokawa Y (2026). [PMID: 41808608](https://pubmed.ncbi.nlm.nih.gov/41808608/). *Int Forum Allergy Rhinol*. [Case Report / Case Series]
Kim K (2026). [PMID: 41618731](https://pubmed.ncbi.nlm.nih.gov/41618731/). *Laryngoscope*. [Clinical Trial Publication]
Jha N (2026). [PMID: 42084302](https://pubmed.ncbi.nlm.nih.gov/42084302/). *Otolaryngol Head Neck Surg*. [Clinical Trial Publication]
Guerrero-García T (2026). [PMID: 42028107](https://pubmed.ncbi.nlm.nih.gov/42028107/). *Plast Reconstr Surg Glob Open*. [Other]
Dong D (2026). [PMID: 39323204](https://pubmed.ncbi.nlm.nih.gov/39323204/). *Comput Methods Biomech Biomed Engin*. [Basic Science / Preclinical]
Lechien JR (2026). [PMID: 39394329](https://pubmed.ncbi.nlm.nih.gov/39394329/). *Eur Arch Otorhinolaryngol*. [Epidemiology / Natural History]
Rees A (2026). [PMID: 41099754](https://pubmed.ncbi.nlm.nih.gov/41099754/). *Strabismus*. [Case Report / Case Series]