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A malignant mesenchymal neoplasm that affects the uterine corpus, and rarely, the ovaries, cervix, and vagina. In the uterine corpus it is classified as low grade or high grade endometrial stromal sarcoma. In the remainder of the anatomic sites it is classified as low grade endometrioid stromal sarcoma.
Biomarker and diagnostic research for endometrioid stromal sarcoma has been reported in the published literature.
3 clinical trials registered, 1 recruiting. Interventions under study include drug therapy and biologic therapy. Pipeline includes 3 PHASE2. Research is sponsored by a mix of industry and academic institutions.
133 publications have been identified in PubMed for endometrioid stromal sarcoma. Research spans Case Report / Case Series (45%), Review / Meta-Analysis (21%), and Diagnostic / Biomarker (11%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 60 |
Data assembled from 4 of 12 sources · Last updated Sep 20, 2026, 11:12 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Research summaries | 28 | 21% |
Testing and diagnosis research | 14 | 11% |
Disease patterns and progression | 13 | 10% |
Other research | 8 | 6% |
Laboratory research | 6 | 5% |
Clinical study results | 4 | 3% |
Hartwich TMP (2026). [PMID: 41591910](https://pubmed.ncbi.nlm.nih.gov/41591910/). *Proc Natl Acad Sci U S A*. [Basic Science / Preclinical]
Xu B (2026). [PMID: 41491971](https://pubmed.ncbi.nlm.nih.gov/41491971/). *Eur J Med Res*. [Clinical Trial Publication]
Bottazzi S (2026). [PMID: 40704674](https://pubmed.ncbi.nlm.nih.gov/40704674/). *Br J Radiol*. [Review / Meta-Analysis]
Arciuolo D (2026). [PMID: 41706043](https://pubmed.ncbi.nlm.nih.gov/41706043/). *J Pathol*. [Basic Science / Preclinical]
Chiang S (2026). [PMID: 41086256](https://pubmed.ncbi.nlm.nih.gov/41086256/). *Annu Rev Pathol*. [Review / Meta-Analysis]
Watson GA (2026). [PMID: 42143439](https://pubmed.ncbi.nlm.nih.gov/42143439/). *Int J Gynecol Cancer*. [Review / Meta-Analysis]
Vaccarezza M (2026). [PMID: 40906052](https://pubmed.ncbi.nlm.nih.gov/40906052/). *J Endocrinol Invest*. [Review / Meta-Analysis]
Bahati AM (2026). [PMID: 41694899](https://pubmed.ncbi.nlm.nih.gov/41694899/). *Cureus*. [Case Report / Case Series]
Pilkington T (2026). [PMID: 41369044](https://pubmed.ncbi.nlm.nih.gov/41369044/). *Am J Surg Pathol*. [Case Report / Case Series]
Wang L (2026). [PMID: 41285250](https://pubmed.ncbi.nlm.nih.gov/41285250/). *Mod Pathol*. [Diagnostic / Biomarker]
AI-curated news mentioning endometrioid stromal sarcoma
Updated Apr 6, 2026
A rare case study highlights the malignant transformation of endometriosis into extrauterine endometrial stromal sarcoma. This finding underscores the need for further research into the oncogenic potential of endometriosis.