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eosinophilic granuloma - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

eosinophilic granuloma

MONDO:0020517

Also known as:Monostotic Langerhans cell histiocytosischronic and localised Langerhans cell histiocytosischronic and localized Langerhans cell histiocytosis

Overview

A clinical variant of Langerhans cell histiocytosis characterized by unifocal involvement of a bone (most often), skin, or lung. Patients are usually older children or adults usually presenting with a lytic bone lesion. The etiology is unknown. Morphologically, eosinophilic granuloma is characterized by the presence of Langerhans cells in a characteristic milieu which includes histiocytes, eosinophils, neutrophils, and small, mature lymphocytes.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for eosinophilic granuloma.

42 publications have been identified in PubMed for eosinophilic granuloma. Research spans Case Report / Case Series (69%), Review / Meta-Analysis (21%), and Clinical Trial Publication (5%).

Research Type	Count	% of Total
Patient case studies	29	69%

Data assembled from 3 of 12 sources · Last updated Sep 18, 2026, 4:11 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:99871

Questions for Your Care Team

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eosinophilic granuloma

Overview

Research Landscape

Medical References

External Resources

Orphanet

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Recent Publications