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epilepsy of infancy with migrating focal seizures (EIMFS) - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

epilepsy of infancy with migrating focal seizures

MONDO:0100025

Also known as:EIMFS

Overview

This syndrome is characterized by onset of refractory focal seizures in the first year of life, with associated severe encephalopathy. Focal seizures arise independently in both hemispheres and can migrate from one cortical region to another randomly but consecutively in the same seizure. Seizures are often prolonged with episodes of status epilepticus. Prognosis is poor with severe neurological disability and reduced life expectancy, although a milder evolution has been reported in a few children.

Diagnosis

Biomarker and diagnostic research for epilepsy of infancy with migrating focal seizures has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for epilepsy of infancy with migrating focal seizures.

16 publications have been identified in PubMed for epilepsy of infancy with migrating focal seizures. Research spans Case Report / Case Series (25%), Review / Meta-Analysis (19%), and Basic Science / Preclinical (19%).

Research Type	Count	% of Total
Patient case studies	4	25%

Data assembled from 2 of 12 sources · Last updated Sep 20, 2026, 12:08 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

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epilepsy of infancy with migrating focal seizures

Overview

Diagnosis

Research Landscape

Medical References

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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