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Ewing sarcoma of bone - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

Ewing sarcoma of bone

MONDO:0002625

Also known as:Ewing's sarcoma of boneEwing's sarcoma, osseousEwing's sarcoma/bone peripheral primitive neuroectodermal tumor

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Overview

A small round cell bone tumor that lacks morphologic, immunohistochemical, and electron microscopic evidence of neuroectodermal differentiation. It represents one of the two ends of the spectrum called Ewing sarcoma/peripheral neuroectodermal tumor. It often affects the diaphysis or metaphyseal-diaphyseal portion of long bones. Clinical findings include pain and a mass in the involved area. fever, anemia, leukocytosis, and an increased sedimentation rate are often seen. X-ray examination reveals osteolytic lesions. The prognosis depends on the stage, anatomic location, and size of the tumor.

Clinical Trials6 registered · 3 recruiting

Diagnosis

Biomarker and diagnostic research for Ewing sarcoma of bone has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

6 clinical trials registered, 3 recruiting. Interventions under study include other interventions, drug therapy, and procedural interventions. Pipeline includes 1 PHASE2, 1 PHASE1, 1 NA. Research is primarily sponsored by academic and government institutions.

NCT ID	Title	Phase	Sponsor	Status
[NCT06935864](https://clinicaltrials.gov/study/NCT06935864)

Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 6:53 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

Questions for Your Care Team

→Are any of the 6 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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Research Type	Count	% of Total
Patient case studies	83	57%
Research summaries	18	12%
Disease patterns and progression	14	10%
Laboratory research	11	8%
Clinical study results	9	6%
Testing and diagnosis research	8	5%
New treatment approaches	3	2%

Kisho

Ewing sarcoma of bone

Overview

Diagnosis

Research Landscape

Medical References

Questions for Your Care Team

Questions for Your Care Team

Recent Publications

Latest News & Developments

Presumptive Ewing Sarcoma of the Jejunum Presenting with Metastatic Disease: A Case Report and Focused Narrative Review.

Durable clinical and immunologic response to an off-the-shelf EWSR1-FLI1 peptide vaccine in metastatic Ewing sarcoma.

Evaluation of limb function after treatment with chemotherapy and carbon ion radiotherapy for Ewing sarcoma of the scapula: A report of three cases.

Ewing sarcoma of bone

Overview

Diagnosis

Research Landscape

Medical References

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Recent Publications

Latest News & Developments

Presumptive Ewing Sarcoma of the Jejunum Presenting with Metastatic Disease: A Case Report and Focused Narrative Review.

Durable clinical and immunologic response to an off-the-shelf EWSR1-FLI1 peptide vaccine in metastatic Ewing sarcoma.

Evaluation of limb function after treatment with chemotherapy and carbon ion radiotherapy for Ewing sarcoma of the scapula: A report of three cases.