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dedifferentiated chondrosarcoma (DDCHS) - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

dedifferentiated chondrosarcoma

MONDO:0005013

Also known as:DDCHS

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Overview

An aggressive morphologic variant of chondrosarcoma. It is composed of a low grade chondrosarcoma and a high grade non-cartilagenous sarcomatous component. Due to the aggressive nature of the disease, its prognosis is poor.

Clinical Trials4 registered

Diagnosis

Biomarker and diagnostic research for dedifferentiated chondrosarcoma has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

4 clinical trials registered. Interventions under study include drug therapy, other interventions, procedural interventions, and biologic therapy. Pipeline includes 3 PHASE2. Research is primarily sponsored by academic and government institutions.

36 publications have been identified in PubMed for dedifferentiated chondrosarcoma. Research spans Case Report / Case Series (36%), Clinical Trial Publication (17%), and Epidemiology / Natural History (14%).

Research Type	Count	% of Total
Patient case studies	13

Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 3:29 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

Questions for Your Care Team

→Are any of the 4 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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dedifferentiated chondrosarcoma

Overview

Diagnosis

Research Landscape

Medical References

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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