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Biomarker and diagnostic research for F12-associated cold autoinflammatory syndrome has been reported in the published literature.
Estimated prevalence: <1 in 1,000,000 (VERY_RARE).
No clinical trials have been registered for F12-associated cold autoinflammatory syndrome.
21 publications have been identified in PubMed for F12-associated cold autoinflammatory syndrome. Research spans Case Report / Case Series (43%), Review / Meta-Analysis (14%), and Basic Science / Preclinical (14%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 9 | 43% |
Data assembled from 3 of 12 sources · Last updated Sep 18, 2026, 7:14 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Common questions about F12-associated cold autoinflammatory syndrome
Research summaries
3 |
14% |
Laboratory research | 3 | 14% |
New treatment approaches | 2 | 10% |
Other research | 1 | 5% |
Testing and diagnosis research | 1 | 5% |
Clinical study results | 1 | 5% |
Disease patterns and progression | 1 | 5% |
Snouwaert JN (2026). [PMID: 41797712](https://pubmed.ncbi.nlm.nih.gov/41797712/). *JCI Insight*. [Basic Science / Preclinical]
Kato C (2026). [PMID: 41263512](https://pubmed.ncbi.nlm.nih.gov/41263512/). *Mod Rheumatol*. [Clinical Trial Publication]
Nicholas T (2026). [PMID: 41451028](https://pubmed.ncbi.nlm.nih.gov/41451028/). *JAAD Case Rep*. [Case Report / Case Series]
Lizama-Muñoz A (2026). [PMID: 42099593](https://pubmed.ncbi.nlm.nih.gov/42099593/). *Front Immunol*. [Case Report / Case Series]
Bouramtane A (2026). [PMID: 41261519](https://pubmed.ncbi.nlm.nih.gov/41261519/). *Int J Immunogenet*. [Review / Meta-Analysis]
Levin JA (2026). [PMID: 41961992](https://pubmed.ncbi.nlm.nih.gov/41961992/). *A A Pract*. [Case Report / Case Series]
Aslani N (2026). [PMID: 42163195](https://pubmed.ncbi.nlm.nih.gov/42163195/). *BMC Pediatr*. [Case Report / Case Series]
Ruíz-Santana JE (2026). [PMID: 42157874](https://pubmed.ncbi.nlm.nih.gov/42157874/). *Case Rep Med*. [Case Report / Case Series]
Zhang CY (2025). [PMID: 39958558](https://pubmed.ncbi.nlm.nih.gov/39958558/). *World J Gastrointest Oncol*. [Other]
Ruan Y (2025). [PMID: 40852416](https://pubmed.ncbi.nlm.nih.gov/40852416/). *Front Pediatr*. [Case Report / Case Series]