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facial paresis, hereditary congenital, 1 (HCFP1) - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

facial paresis, hereditary congenital, 1

MONDO:0024466

Also known as:HCFP1Mobius syndrome 2Mobius syndrome 2, formerly

Find Clinical TrialsTrials

Overview

GeneticsAutosomal dominant

Clinical Trials1 registered · 1 recruiting

Clinical Presentation

Built from Human Phenotype Ontology (HPO) phenotype annotations and GeneReviews clinical descriptions. Features represent findings documented across known cases — not an exhaustive list of possible symptoms.

Features include: Facial palsy, Weakness of orbicularis oculi muscle, and Decreased corneal reflex.

Organ System	Phenotype Count	Example Features
Head and neck	1	Facial palsy
Muscles

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

1 clinical trial registered, 1 recruiting. Interventions under study include other interventions. Research is primarily sponsored by academic and government institutions.

17 publications have been identified in PubMed for facial paresis, hereditary congenital, 1. Research spans Review / Meta-Analysis (29%), Case Report / Case Series (24%), and Clinical Trial Publication (24%).

Research Type	Count	% of Total
Research summaries	5	29%

Data assembled from 5 of 12 sources · Last updated Sep 20, 2026, 5:51 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

OMIM

Online Mendelian Inheritance in Man

OMIM:601471

Questions for Your Care Team

→Are any of the 1 active clinical trial a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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facial paresis, hereditary congenital, 1

Overview

Clinical Presentation

Research Landscape

Medical References

External Resources

OMIM

Questions for Your Care Team

Questions for Your Care Team

Explore clinical features

Recent Publications

facial paresis, hereditary congenital, 1

Overview

Clinical Presentation

Research Landscape

Medical References

External Resources

OMIM

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Questions for Your Care Team

Questions for Your Care Team

Explore clinical features

Recent Publications