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Familial developmental dysphasia is described in the ontology definition as a severe form of developmental verbal apraxia. Hearing and intelligence are described as normal. The condition is also known by names including developmental dysphasia familial, developmental language disorder, specific language impairment, and Billard-Toutain-Maheut syndrome. Prevalence is listed in this packet as very rare, at fewer than 1 in 1,000,000 people. Age of onset is not certified in this packet.
No phenotype list is certified in this packet beyond the definition. According to that definition, the condition is characterized by a deficit in spontaneous speech, writing, grammatical judgment, and repetition; defective articulation; a moderate to severe degree of dyspraxia; a reduced use of consonant clusters; and comprehension delay. Hearing and intelligence are described as normal. Frequencies of these features are not given in this packet.
Data assembled from 6 of 12 sources · Last updated Nov 3, 2026, 1:03 PM UTC
Online Mendelian Inheritance in Man
European rare disease database
Genetic and Rare Diseases Info Center
The packet lists an autosomal dominant inheritance pattern. No associated genes are listed, and no molecular mechanism is certified in this packet, so the genetic basis is unknown here.
Diagnostic methods are not certified in this packet. The definition's description of speech, writing, and language features, with normal hearing and intelligence, reflects how the condition is characterized rather than a diagnostic criterion.
No foundational therapies, approved treatments, or management guidance are certified in this packet, so the absence of such information here does not indicate that none exist. Clinical trial records listed for related search terms include behavioral and language-training studies in developmental language disorder, which are investigational in nature.
32 trials found
Prognosis is not certified in this packet.
Several active clinical trial records are certified under this condition name. Examples include NCT04902508, titled Evaluation of an Explicit Approach (not applicable phase, active not recruiting); NCT06660108, titled Molecular Basis of Language Development and Associated Disorders (not applicable phase, recruiting); and NCT06156865, titled Using Neuroimaging and Behavioral Assessments to Understand Late Talking (not applicable phase, recruiting). Active clinical trials for this condition are listed on ClinicalTrials.gov.