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complex regional pain syndrome type 1 - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

complex regional pain syndrome type 1

MONDO:0011441

Also known as:AlgodystrophyCRPS ICRPS1

Find Clinical TrialsTrials

Overview

Complex regional pain syndrome type 1 (CRPS1) is a form of complex regional pain syndrome in which the pain is disproportionate to any known inciting event and is characterized by continuous pain, allodynia, or hyperalgesia as well as edema, coloration (changes in skin blood flow), or abnormal sudomotor activity in the region of pain. Onset of CRPS1 symptoms may occur within a few days to a month after an injury or trauma to the affected limb.

Clinical Trials4 registered · 1 recruiting

Patient Orgs1 organizations · Reflex Sympathetic Dystrophy Syndrome Association (RSDSA)

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

4 clinical trials registered, 1 recruiting. Interventions under study include medical devices, drug therapy, and other interventions. Pipeline includes 1 PHASE4, 2 NA. Research is sponsored by a mix of industry and academic institutions.

34 publications have been identified in PubMed for complex regional pain syndrome type 1. Research spans Case Report / Case Series (27%), Clinical Trial Publication (24%), and Review / Meta-Analysis (18%).

Research Type	Count	% of Total
Patient case studies	9

Data assembled from 5 of 12 sources · Last updated Sep 19, 2026, 9:40 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Patient Support

Patient Advocacy Groups

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Reflex Sympathetic Dystrophy Syndrome Association (RSDSA)Primary Focus

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Patient Advocacy Groups (PAGs) provide support, resources, and community for patients and caregivers.

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Medical References

External Resources

OMIM

Online Mendelian Inheritance in Man

OMIM:604335

Orphanet

European rare disease database

Orphanet:99995

GARD

Genetic and Rare Diseases Info Center

GARD:16928

Questions for Your Care Team

→Are any of the 4 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→How can I connect with Reflex Sympathetic Dystrophy Syndrome Association (RSDSA) and other patient organizations for support?

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complex regional pain syndrome type 1

Overview

Research Landscape

Patient Support

Patient Advocacy Groups

Medical References

External Resources

OMIM

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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