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complex regional pain syndrome type 2 - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

complex regional pain syndrome type 2

MONDO:0020572

Also known as:CRPS IIComplex regional pain syndrome IIComplex regional pain syndrome, type II

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Overview

Complex regional pain syndrome type 2 (CRPS2), or causalgia is a form of complex regional pain syndrome that develops after damage to a peripheral nerve and is characterized by spontaneous pain, allodynia and hyperalgesia, not necessarily limited to the territory of the injured nerve, as well as at some point, edema, changes in skin blood flow or sudomotor dysfunction in the pain area.

Clinical Trials2 registered · 1 recruiting

Prognosis

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

2 clinical trials registered, 1 recruiting. Interventions under study include drug therapy and other interventions. Pipeline includes 1 PHASE4. Research is primarily sponsored by academic and government institutions.

12 publications have been identified in PubMed for complex regional pain syndrome type 2. Research spans Case Report / Case Series (50%), Review / Meta-Analysis (25%), and Clinical Trial Publication (17%).

Research Type	Count	% of Total
Patient case studies	6

Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 4:31 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:99994

GARD

Genetic and Rare Diseases Info Center

GARD:19727

Questions for Your Care Team

→Are any of the 2 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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complex regional pain syndrome type 2

Overview

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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