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A rare, genetic, skin tumor disorder characterized by childhood-onset of multiple, benign, asymptomatic, white to flesh-colored papules predominantly located on the face, ears, neck and trunk, not associated with systemic organ involvement, associated malignancies or FLCN gene locus mutation.
Features include: Abnormal hair morphology.
Estimated prevalence: <1 in 1,000,000 (VERY_RARE).
No clinical trials have been registered for familial multiple discoid fibromas.
3 publications have been identified in PubMed for familial multiple discoid fibromas. Research spans Review / Meta-Analysis (67%) and Other (33%).
Broniarek I (2026). [PMID: 41896555](https://pubmed.ncbi.nlm.nih.gov/41896555/). *NPJ Genom Med*. [Other]
Gokyayla E (2026). [PMID: 41506187](https://pubmed.ncbi.nlm.nih.gov/41506187/). *An Bras Dermatol*. [Review / Meta-Analysis]
Geilswijk M (2024). [PMID: 39085584](https://pubmed.ncbi.nlm.nih.gov/39085584/). *Eur J Hum Genet*. [Review / Meta-Analysis]
Data assembled from 5 of 12 sources · Last updated Sep 21, 2026, 4:51 AM UTC
Online Mendelian Inheritance in Man
European rare disease database
Genetic and Rare Diseases Info Center