Kisho

Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy

familial temporal lobe epilepsy 6 (ETL6) - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

familial temporal lobe epilepsy 6

MONDO:0014308

Also known as:ETL6familial temporal lobe epilepsy type 6epilepsy, familial temporal lobe, 6

Overview

A temporal lobe epilepsy that has material basis in variation in the chromosome region 3q25-q26.

GeneticsAutosomal dominant

ResearchLimited published research (2 articles)

Clinical Presentation

Built from Human Phenotype Ontology (HPO) phenotype annotations and GeneReviews clinical descriptions. Features represent findings documented across known cases — not an exhaustive list of possible symptoms.

Features include common findings: Febrile seizure (within the age range of 3 months to 6 years), Focal impaired awareness seizure, Bilateral tonic-clonic seizure with focal onset, and Focal aware seizure; and sometimes findings: Status epilepticus.

Organ System	Phenotype Count	Example Features
Brain and nerves	5	Status epilepticus, Febrile seizure (within the age range of 3 months to 6 years), Focal impaired awareness seizure

Prognosis

Phenotype severity distribution: 4 common features.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for familial temporal lobe epilepsy 6.

2 publications have been identified in PubMed for familial temporal lobe epilepsy 6. Research spans Review / Meta-Analysis (50%) and Case Report / Case Series (50%).

Recent Publications

Ni J (2025). [PMID: 40461170](https://pubmed.ncbi.nlm.nih.gov/40461170/). *J Med Genet*. [Review / Meta-Analysis]
Chen Y (2024). [PMID: 40217319](https://pubmed.ncbi.nlm.nih.gov/40217319/). *Acta Epileptol*. [Case Report / Case Series]

Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 6:55 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

OMIM

Online Mendelian Inheritance in Man

OMIM:615697

GARD

Genetic and Rare Diseases Info Center

GARD:18281

Questions for Your Care Team

→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

← Back to All Diseases

familial temporal lobe epilepsy 6

Overview

Clinical Presentation

Prognosis

Research Landscape

Recent Publications

Medical References

External Resources

OMIM

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Explore clinical features