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A neoplasm composed of spindle to ovoid cells which have morphologic and immunophenotypic characteristics of follicular dendritic cells. It affects lymph nodes and other sites including the tonsils, gastrointestinal tract, spleen, liver, soft tissues, skin, and oral cavity. It usually behaves as a low grade sarcoma. Treatment options include complete surgical removal of the tumor with or without adjuvant chemotherapy or radiotherapy. Recurrences have been reported in up to half of the cases.
Biomarker and diagnostic research for follicular dendritic cell sarcoma has been reported in the published literature.
No clinical trials have been registered for follicular dendritic cell sarcoma.
85 publications have been identified in PubMed for follicular dendritic cell sarcoma. Research spans Case Report / Case Series (65%), Review / Meta-Analysis (13%), and Other (8%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 55 | 65% |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 1:00 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
11 |
13% |
Other research | 7 | 8% |
Testing and diagnosis research | 5 | 6% |
Laboratory research | 5 | 6% |
Disease patterns and progression | 2 | 2% |
Geng J (2026). [PMID: 41771039](https://pubmed.ncbi.nlm.nih.gov/41771039/). *Clin Nucl Med*. [Case Report / Case Series]
Meng R (2026). [PMID: 42130636](https://pubmed.ncbi.nlm.nih.gov/42130636/). *Front Oncol*. [Case Report / Case Series]
Chen QQ (2026). [PMID: 41264975](https://pubmed.ncbi.nlm.nih.gov/41264975/). *Ann Diagn Pathol*. [Review / Meta-Analysis]
Glanz H (2026). [PMID: 41940675](https://pubmed.ncbi.nlm.nih.gov/41940675/). *J Pediatr Hematol Oncol*. [Case Report / Case Series]
Geng H (2026). [PMID: 42099138](https://pubmed.ncbi.nlm.nih.gov/42099138/). *Curr Cancer Drug Targets*. [Case Report / Case Series]
Su JJ (2026). [PMID: 42063541](https://pubmed.ncbi.nlm.nih.gov/42063541/). *iScience*. [Epidemiology / Natural History]
Rousselot A (2026). [PMID: 41535611](https://pubmed.ncbi.nlm.nih.gov/41535611/). *J Hematop*. [Case Report / Case Series]
Lu J (2026). [PMID: 41904543](https://pubmed.ncbi.nlm.nih.gov/41904543/). *Infect Agent Cancer*. [Case Report / Case Series]
Hassan F (2026). [PMID: 41943444](https://pubmed.ncbi.nlm.nih.gov/41943444/). *Appl Immunohistochem Mol Morphol*. [Case Report / Case Series]
Kaderi ASA (2026). [PMID: 42023196](https://pubmed.ncbi.nlm.nih.gov/42023196/). *Indian J Surg Oncol*. [Case Report / Case Series]
AI-curated news mentioning follicular dendritic cell sarcoma
Updated Jun 5, 2026
A recent study highlights increased mucocutaneous FDG activity in paraneoplastic pemphigus linked to follicular dendritic cell sarcoma, which has transformed from Castleman disease. This research may provide insights into the complex interactions between these rare conditions.
A multicenter study investigates the clinicopathological characteristics of intra-abdominal follicular dendritic cell sarcomas, providing valuable insights into this rare disease. The findings may enhance understanding and inform future research directions.