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A gastrin-producing neuroendocrine tumor. It is usually located in the pancreas but it is also found at other anatomic sites, including the stomach and small intestine.
Biomarker and diagnostic research for gastrin-producing neuroendocrine tumor has been reported in the published literature.
2 FDA-approved treatments are available for gastrin-producing neuroendocrine tumor, including secreflo (SECREFLO, approved 2002) and HUMAN SECRETIN (CHIRHOSTIM, approved 2004). An additional 1 compound holds orphan drug designation.
Brand Name | Generic Name | Mechanism | Approved | Market Status |
|---|---|---|---|---|
2 clinical trials registered. Interventions under study include drug therapy and other interventions. Pipeline includes 1 PHASE2. Research is primarily sponsored by academic and government institutions.
49 publications have been identified in PubMed for gastrin-producing neuroendocrine tumor. Research spans Case Report / Case Series (39%), Review / Meta-Analysis (27%), and Basic Science / Preclinical (10%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 19 |
Data assembled from 4 of 12 sources · Last updated Sep 20, 2026, 11:13 AM UTC
CHIRHOSTIM |
HUMAN SECRETIN |
— |
2004 |
Available |
SECREFLO | — | — | 2002 | Available |
The following drugs have received orphan drug designation from the FDA for gastrin-producing neuroendocrine tumor. Orphan designation reflects regulatory interest and does not indicate approval for treatment.
Brand Name | Generic Name | Sponsor | Designated | Exclusivity End | Designation Status |
|---|---|---|---|---|---|
Secreflo | Synthetic porcine secretin | ChiRhoClin, Inc. | 1999 | 2009 | Designated (drug approved for other indication) |
Gene therapy approaches for gastrin-producing neuroendocrine tumor have been reported in the published literature.
2 trials found
Research summaries | 13 | 27% |
Laboratory research | 5 | 10% |
Disease patterns and progression | 5 | 10% |
Testing and diagnosis research | 4 | 8% |
Clinical study results | 2 | 4% |
New treatment approaches | 1 | 2% |
Uccella S (2026). [PMID: 41273419](https://pubmed.ncbi.nlm.nih.gov/41273419/). *Virchows Archiv : an international journal of pathology*. [Review / Meta-Analysis]
Stevens KJ (2026). [PMID: 31613505](https://pubmed.ncbi.nlm.nih.gov/31613505/). *Unknown Journal*. [Diagnostic / Biomarker]
Rogalidou M (2026). [PMID: 41736231](https://pubmed.ncbi.nlm.nih.gov/41736231/). *Clinical and experimental pediatrics*. [Review / Meta-Analysis]
Prosapio JG (2026). [PMID: 30521243](https://pubmed.ncbi.nlm.nih.gov/30521243/). *Unknown Journal*. [Basic Science / Preclinical]
Iwamoto H (2026). [PMID: 41809843](https://pubmed.ncbi.nlm.nih.gov/41809843/). *Diabetology international*. [Epidemiology / Natural History]
Gaujoux S (2026). [PMID: 41862416](https://pubmed.ncbi.nlm.nih.gov/41862416/). *World J Surg*. [Epidemiology / Natural History]
Lin L (2026). [PMID: 42008494](https://pubmed.ncbi.nlm.nih.gov/42008494/). *J Vis Exp*. [Case Report / Case Series]
Miyata T (2026). [PMID: 41945253](https://pubmed.ncbi.nlm.nih.gov/41945253/). *Clin J Gastroenterol*. [Case Report / Case Series]
Mariën L (2026). [PMID: 42140697](https://pubmed.ncbi.nlm.nih.gov/42140697/). *J Neuroendocrinol*. [Epidemiology / Natural History]
Helbing A (2026). [PMID: 28722872](https://pubmed.ncbi.nlm.nih.gov/28722872/). *Unknown Journal*. [Review / Meta-Analysis]