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glioma susceptibility 3 - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

glioma susceptibility 3

MONDO:0013093

Also known as:BRCA2 malignant gliomaglioblastoma 3glioma susceptibility type 3

Overview

Any malignant glioma in which the cause of the disease is a mutation in the BRCA2 gene.

GeneticsAutosomal recessive

Clinical Presentation

Built from Human Phenotype Ontology (HPO) phenotype annotations and GeneReviews clinical descriptions. Features represent findings documented across known cases — not an exhaustive list of possible symptoms.

Features include common findings: Glioblastoma multiforme, Acute myeloid leukemia, and Nephroblastoma; and sometimes findings: Astrocytoma, T-cell acute lymphoblastic leukemias, B Acute Lymphoblastic Leukemia, and Medulloblastoma.

Organ System	Phenotype Count	Example Features
Kidneys and urinary system	1	Nephroblastoma

Explore clinical features

Diagnosis

Biomarker and diagnostic research for glioma susceptibility 3 has been reported in the published literature.

Prognosis

Phenotype severity distribution: 3 common features.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for glioma susceptibility 3.

117 publications have been identified in PubMed for glioma susceptibility 3. Research spans Basic Science / Preclinical (26%), Diagnostic / Biomarker (22%), and Epidemiology / Natural History (15%).

Research Type	Count	% of Total
Laboratory research	31	26%

Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 11:55 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

OMIM

Online Mendelian Inheritance in Man

OMIM:613029

Questions for Your Care Team

→Should my partner and I meet with a genetic counselor to discuss carrier status and family planning?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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glioma susceptibility 3

Overview

Clinical Presentation

Explore clinical features

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

OMIM

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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