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Features include always present findings: Decreased circulating cortisol level, Increased circulating ACTH level, and Hyperpigmentation of the skin; and very common findings: Recurrent hypoglycemia. 6 total HPO annotations.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Hormones | 1 | Decreased circulating cortisol level |
Biomarker and diagnostic research for glucocorticoid deficiency 3 has been reported in the published literature.
Phenotype severity distribution: 3 always present features, 1 very common feature, 1 common feature.
No clinical trials have been registered for glucocorticoid deficiency 3.
187 publications have been identified in PubMed for glucocorticoid deficiency 3. Research spans Basic Science / Preclinical (26%), Case Report / Case Series (24%), and Review / Meta-Analysis (18%).
Research Type | Count | % of Total |
|---|---|---|
Laboratory research | 48 | 26% |
Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 6:54 PM UTC
Online Mendelian Inheritance in Man
Genetic and Rare Diseases Info Center
Lab test results
1 |
Decreased circulating cortisol level |
Skin | 1 | Hyperpigmentation of the skin |
44 |
24% |
Research summaries | 33 | 18% |
Clinical study results | 32 | 17% |
Disease patterns and progression | 24 | 13% |
Testing and diagnosis research | 6 | 3% |
Xu WS (2026). [PMID: 42236459](https://pubmed.ncbi.nlm.nih.gov/42236459/). *Zhonghua Jie He He Hu Xi Za Zhi*. [Case Report / Case Series]
Mathara Diddhenipothage SAD (2026). [PMID: 41879139](https://pubmed.ncbi.nlm.nih.gov/41879139/). *Clin Endocrinol (Oxf)*. [Case Report / Case Series]
di Filippo L (2026). [PMID: 42213233](https://pubmed.ncbi.nlm.nih.gov/42213233/). *Pituitary*. [Review / Meta-Analysis]
Macfarlane E (2026). [PMID: 41903788](https://pubmed.ncbi.nlm.nih.gov/41903788/). *Bone*. [Review / Meta-Analysis]
Al-Agha AE (2026). [PMID: 41807209](https://pubmed.ncbi.nlm.nih.gov/41807209/). *J Natl Med Assoc*. [Review / Meta-Analysis]
Franz J (2026). [PMID: 41692820](https://pubmed.ncbi.nlm.nih.gov/41692820/). *Sci Rep*. [Basic Science / Preclinical]
Fatehpoor S (2026). [PMID: 41856693](https://pubmed.ncbi.nlm.nih.gov/41856693/). *BMJ Case Rep*. [Case Report / Case Series]
Weide R (2026). [PMID: 41697935](https://pubmed.ncbi.nlm.nih.gov/41697935/). *Oncol Res Treat*. [Epidemiology / Natural History]
Murphy C (2026). [PMID: 41894886](https://pubmed.ncbi.nlm.nih.gov/41894886/). *Neuromuscul Disord*. [Case Report / Case Series]
Munarin J (2026). [PMID: 41976932](https://pubmed.ncbi.nlm.nih.gov/41976932/). *J Clin Med*. [Diagnostic / Biomarker]