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A glioma arising from the central nervous system. This category includes diffuse astrocytoma, ependymoma, oligodendroglioma, and oligoastrocytoma.
Biomarker and diagnostic research for grade II glioma has been reported in the published literature.
11 clinical trials registered, 6 recruiting. Interventions under study include drug therapy, other interventions, procedural interventions, and biologic therapy. Pipeline includes 2 PHASE2, 5 PHASE1, 2 EARLY_PHASE1. Research is sponsored by a mix of industry and academic institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT06636162](https://clinicaltrials.gov/study/NCT06636162) |
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 6:21 PM UTC
Window of Opportunity Study of DSP-0390 in Gliomas |
EARLY_PHASE1 |
Washington University School of Medicine |
RECRUITING |
[NCT04623931](https://clinicaltrials.gov/study/NCT04623931) | Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas | PHASE2 | M.D. Anderson Cancer Center | RECRUITING |
[NCT04485559](https://clinicaltrials.gov/study/NCT04485559) | Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021) | PHASE1 | University of California, San Francisco | RECRUITING |
[NCT04479696](https://clinicaltrials.gov/study/NCT04479696) | Customized Neuro-Imaging Referenced Symptom Video for the Reduction of Patient and Caregiver Anxiety Around Radiation Treatment for Brain Tumors | NA | M.D. Anderson Cancer Center | RECRUITING |
[NCT04540107](https://clinicaltrials.gov/study/NCT04540107) | Serial MR Imaging and MR Spectroscopic Imaging for the Characterization of Lower Grade Glioma | PHASE1 | Susan Chang | RECRUITING |
4 publications have been identified in PubMed for grade II glioma. Research spans Review / Meta-Analysis (50%), Diagnostic / Biomarker (25%), and Clinical Trial Publication (25%).
Badve C (2025). [PMID: 40338482](https://pubmed.ncbi.nlm.nih.gov/40338482/). *J Neurooncol*. [Review / Meta-Analysis]
Falcão L (2025). [PMID: 40032671](https://pubmed.ncbi.nlm.nih.gov/40032671/). *Neurosurg Rev*. [Review / Meta-Analysis]
Wu W (2024). [PMID: 39850400](https://pubmed.ncbi.nlm.nih.gov/39850400/). *Pol J Radiol*. [Diagnostic / Biomarker]
Xie R (2024). [PMID: 39902134](https://pubmed.ncbi.nlm.nih.gov/39902134/). *Front Oncol*. [Clinical Trial Publication]