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Hemoglobin E disease (HbE) is a hemoglobinopathy characterized by production of abnormal variant hemoglobin known as hemoglobin E, with a generally benign, asymptomatic presentation.
Biomarker and diagnostic research for hemoglobin E disease has been reported in the published literature.
Estimated prevalence: Unknown (Unknown prevalence).
No clinical trials have been registered for hemoglobin E disease.
11 publications have been identified in PubMed for hemoglobin E disease. Research spans Epidemiology / Natural History (55%), Case Report / Case Series (18%), and Diagnostic / Biomarker (9%).
Research Type | Count | % of Total |
|---|---|---|
Disease patterns and progression | 6 | 55% |
Data assembled from 3 of 12 sources · Last updated Sep 18, 2026, 5:00 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
2 |
18% |
Testing and diagnosis research | 1 | 9% |
Clinical study results | 1 | 9% |
Laboratory research | 1 | 9% |
Tangwerapornpong C (2026). [PMID: 41982550](https://pubmed.ncbi.nlm.nih.gov/41982550/). *Front Med (Lausanne)*. [Diagnostic / Biomarker]
Malasai K (2026). [PMID: 41612739](https://pubmed.ncbi.nlm.nih.gov/41612739/). *Clinical and translational science*. [Epidemiology / Natural History]
Rukwong P (2025). [PMID: 40888401](https://pubmed.ncbi.nlm.nih.gov/40888401/). *Annals of medicine*. [Epidemiology / Natural History]
Minhas AM (2025). [PMID: 40661155](https://pubmed.ncbi.nlm.nih.gov/40661155/). *Case reports in hematology*. [Case Report / Case Series]
Thwe SM (2025). [PMID: 40919402](https://pubmed.ncbi.nlm.nih.gov/40919402/). *Clinical case reports*. [Epidemiology / Natural History]
Lertsakulbunlue S (2025). [PMID: 40129579](https://pubmed.ncbi.nlm.nih.gov/40129579/). *Anemia*. [Basic Science / Preclinical]
Singh P (2025). [PMID: 41322744](https://pubmed.ncbi.nlm.nih.gov/41322744/). *Cureus*. [Case Report / Case Series]
Pornratananont G (2025). [PMID: 40441082](https://pubmed.ncbi.nlm.nih.gov/40441082/). *Stem cell research*. [Clinical Trial Publication]
Sirilert S (2024). [PMID: 38700018](https://pubmed.ncbi.nlm.nih.gov/38700018/). *International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics*. [Epidemiology / Natural History]
Anuruksuwan P (2024). [PMID: 38234105](https://pubmed.ncbi.nlm.nih.gov/38234105/). *International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics*. [Epidemiology / Natural History]