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Hepatoportal sclerosis (HPS) is a rare disorder characterized by sclerosis of the intrahepatic portal veins, non-cirrhotic portal hypertension, asymptomatic splenomegaly and recurrent variceal bleeding.
Biomarker and diagnostic research for hepatoportal sclerosis has been reported in the published literature.
Estimated prevalence: Unknown (Unknown prevalence).
No clinical trials have been registered for hepatoportal sclerosis.
30 publications have been identified in PubMed for hepatoportal sclerosis. Research spans Review / Meta-Analysis (30%), Case Report / Case Series (23%), and Diagnostic / Biomarker (17%).
Research Type | Count | % of Total |
|---|---|---|
Research summaries | 9 | 30% |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 5:31 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
7 |
23% |
Testing and diagnosis research | 5 | 17% |
Disease patterns and progression | 4 | 13% |
Laboratory research | 3 | 10% |
Other research | 1 | 3% |
Clinical study results | 1 | 3% |
Hernández-Gea V (2026). [PMID: 42191459](https://pubmed.ncbi.nlm.nih.gov/42191459/). *J Hepatol*. [Review / Meta-Analysis]
Martineau R (2026). [PMID: 41866303](https://pubmed.ncbi.nlm.nih.gov/41866303/). *Prenat Diagn*. [Review / Meta-Analysis]
Rajakannu M (2026). [PMID: 42003500](https://pubmed.ncbi.nlm.nih.gov/42003500/). *Pediatr Transplant*. [Case Report / Case Series]
Khandakar B (2026). [PMID: 41297617](https://pubmed.ncbi.nlm.nih.gov/41297617/). *Hum Pathol*. [Case Report / Case Series]
Takahashi K (2026). [PMID: 41568615](https://pubmed.ncbi.nlm.nih.gov/41568615/). *Hepatol Res*. [Other]
Agrawal R (2026). [PMID: 41902447](https://pubmed.ncbi.nlm.nih.gov/41902447/). *Histopathology*. [Case Report / Case Series]
Merk J (2026). [PMID: 41406992](https://pubmed.ncbi.nlm.nih.gov/41406992/). *Pediatrics*. [Case Report / Case Series]
Wang X (2026). [PMID: 42023120](https://pubmed.ncbi.nlm.nih.gov/42023120/). *Front Med (Lausanne)*. [Diagnostic / Biomarker]
de Broucker C (2026). [PMID: 41492317](https://pubmed.ncbi.nlm.nih.gov/41492317/). *JHEP Rep*. [Diagnostic / Biomarker]
Hernandez-Gea V (2026). [PMID: 42191125](https://pubmed.ncbi.nlm.nih.gov/42191125/). *Hepatology*. [Diagnostic / Biomarker]