Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy
Hidrotic ectodermal dysplasia, Christianson-Fourie type is a rare ectodermal dysplasia syndrome characterized by tricho- and onychodysplasia in association with cardiac rhythm abnormalities. Patients present with sparse scalp hair and eyelashes, absent or sparse eyebrows, dystrophic thickened nails (on fingers distal end may be lifted from the nail bed) and supraventricular tachicardia or sinus bradicardia.
Biomarker and diagnostic research for hidrotic ectodermal dysplasia, Christianson-Fourie type has been reported in the published literature.
Estimated prevalence: <1 in 1,000,000 (VERY_RARE).
No clinical trials have been registered for hidrotic ectodermal dysplasia, Christianson-Fourie type.
155 publications have been identified in PubMed for hidrotic ectodermal dysplasia, Christianson-Fourie type. Research spans Review / Meta-Analysis (54%), Basic Science / Preclinical (19%), and Case Report / Case Series (17%).
Research Type | Count | % of Total |
|---|---|---|
Research summaries | 74 | 54% |
Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 2:58 PM UTC
Online Mendelian Inheritance in Man
European rare disease database
Genetic and Rare Diseases Info Center
Laboratory research |
26 |
19% |
Patient case studies | 24 | 17% |
Disease patterns and progression | 6 | 4% |
Other research | 4 | 3% |
Testing and diagnosis research | 3 | 2% |
New treatment approaches | 1 | 1% |
Xu Y (2026). [PMID: 41640519](https://pubmed.ncbi.nlm.nih.gov/41640519/). *Front Med (Lausanne)*. [Case Report / Case Series]
Martínez-García JJ (2026). [PMID: 42166395](https://pubmed.ncbi.nlm.nih.gov/42166395/). *Am J Case Rep*. [Case Report / Case Series]
Zhu T (2026). [PMID: 42040894](https://pubmed.ncbi.nlm.nih.gov/42040894/). *Hum Mutat*. [Basic Science / Preclinical]
Kocak Eker H (2026). [PMID: 41854160](https://pubmed.ncbi.nlm.nih.gov/41854160/). *Clin Genet*. [Basic Science / Preclinical]
Amado C (2026). [PMID: 40975490](https://pubmed.ncbi.nlm.nih.gov/40975490/). *Ann Allergy Asthma Immunol*. [Review / Meta-Analysis]
Rosen N (2026). [PMID: 40553753](https://pubmed.ncbi.nlm.nih.gov/40553753/). *J Invest Dermatol*. [Basic Science / Preclinical]
Ponomarev AE (2026). [PMID: 41742474](https://pubmed.ncbi.nlm.nih.gov/41742474/). *Stomatologiia (Mosk)*. [Review / Meta-Analysis]
Anderson EN (2026). [PMID: 41468891](https://pubmed.ncbi.nlm.nih.gov/41468891/). *Am J Hum Genet*. [Review / Meta-Analysis]
Dernai J (2026). [PMID: 42229575](https://pubmed.ncbi.nlm.nih.gov/42229575/). *Gene*. [Basic Science / Preclinical]
Torchia D (2026). [PMID: 42241635](https://pubmed.ncbi.nlm.nih.gov/42241635/). *Acta Dermatovenerol Alp Pannonica Adriat*. [Review / Meta-Analysis]