Kisho

Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy

hydatidiform mole - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

hydatidiform mole

MONDO:0006248

Also known as:hydatid molemolar pregnancyHYDM

Find Clinical TrialsTrials

Overview

A gestational trophoblastic disorder characterized by marked enlargement of the chorionic villi, hyperplasia of the villous trophoblastic cells and hydropic changes.

Clinical Trials6 registered · 2 recruiting

Clinical Presentation

Built from Human Phenotype Ontology (HPO) phenotype annotations and GeneReviews clinical descriptions. Features represent findings documented across known cases — not an exhaustive list of possible symptoms.

Features include very common findings: Low red blood cell count (anemia), Nausea and vomiting, Enlarged uterus, and Menometrorrhagia; and sometimes findings: Hyperthyroidism.

Organ System	Phenotype Count	Example Features
Hormones	1	Hyperthyroidism

Diagnosis

Biomarker and diagnostic research for hydatidiform mole has been reported in the published literature.

Prognosis

Phenotype severity distribution: 4 very common features.

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

6 clinical trials registered, 2 recruiting. Interventions under study include other interventions and drug therapy. Pipeline includes 1 NA. Research is primarily sponsored by academic and government institutions.

NCT ID	Title	Phase	Sponsor	Status
[NCT03785574](https://clinicaltrials.gov/study/NCT03785574)

Data assembled from 5 of 12 sources · Last updated Sep 19, 2026, 1:52 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:99927

GARD

Genetic and Rare Diseases Info Center

GARD:10263

Questions for Your Care Team

→Are any of the 6 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

← Back to All Diseases

Research Type	Count	% of Total
Patient case studies	96	42%
Research summaries	34	15%
Disease patterns and progression	32	14%
Testing and diagnosis research	28	12%
Laboratory research	22	10%
Clinical study results	9	4%
Other research	4	2%
New treatment approaches	1	0%

Kisho

hydatidiform mole

Overview

Clinical Presentation

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Questions for Your Care Team

Questions for Your Care Team

Explore clinical features

Recent Publications

Latest News & Developments

Rupture of interstitial ectopic pregnancy secondary to invasive hydatidiform mole with pelvic metastasis in perimenopausal women: A case report.

hydatidiform mole

Overview

Clinical Presentation

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Subtypes

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Explore clinical features

Recent Publications

Latest News & Developments

Rupture of interstitial ectopic pregnancy secondary to invasive hydatidiform mole with pelvic metastasis in perimenopausal women: A case report.