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Features include always present findings: Hydatidiform mole and Female infertility.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Hormones | 1 | Female infertility |
TOP6BL function has not been fully characterized.
Hydatidiform mole, recurrent, 4 is associated with mutations in the TOP6BL gene on chromosome 11.
Genetic testing for TOP6BL is available. Testing is considered confirmatory for diagnosis.
Biomarker and diagnostic research for hydatidiform mole, recurrent, 4 has been reported in the published literature.
Phenotype severity distribution: 2 always present features.
No clinical trials have been registered for hydatidiform mole, recurrent, 4.
14 publications have been identified in PubMed for hydatidiform mole, recurrent, 4. Research spans Basic Science / Preclinical (43%), Review / Meta-Analysis (21%), and Case Report / Case Series (14%).
Research Type | Count | % of Total |
|---|---|---|
Laboratory research | 6 | 43% |
Data assembled from 5 of 12 sources · Last updated Sep 19, 2026, 8:49 PM UTC
Online Mendelian Inheritance in Man
Genetic and Rare Diseases Info Center
Research summaries
3 |
21% |
Patient case studies | 2 | 14% |
Testing and diagnosis research | 1 | 7% |
Disease patterns and progression | 1 | 7% |
New treatment approaches | 1 | 7% |
Cai L (2026). [PMID: 41535518](https://pubmed.ncbi.nlm.nih.gov/41535518/). *Human cell*. [Basic Science / Preclinical]
Wang X (2026). [PMID: 41812828](https://pubmed.ncbi.nlm.nih.gov/41812828/). *Human pathology*. [Basic Science / Preclinical]
Aminbeidokhti M (2025). [PMID: 41256177](https://pubmed.ncbi.nlm.nih.gov/41256177/). *medRxiv : the preprint server for health sciences*. [Basic Science / Preclinical]
Özer L (2025). [PMID: 40908712](https://pubmed.ncbi.nlm.nih.gov/40908712/). *Turkish journal of obstetrics and gynecology*. [Gene Therapy / Novel Therapeutics]
Braga A (2025). [PMID: 40638920](https://pubmed.ncbi.nlm.nih.gov/40638920/). *Obstetrics and gynecology*. [Review / Meta-Analysis]
Bagga R (2025). [PMID: 40319759](https://pubmed.ncbi.nlm.nih.gov/40319759/). *European journal of obstetrics, gynecology, and reproductive biology*. [Epidemiology / Natural History]
Nicheperovich A (2025). [PMID: 39873178](https://pubmed.ncbi.nlm.nih.gov/39873178/). *Disease models & mechanisms*. [Review / Meta-Analysis]
Li P (2025). [PMID: 40322665](https://pubmed.ncbi.nlm.nih.gov/40322665/). *International journal of women's health*. [Case Report / Case Series]
Moon Y (2025). [PMID: 41327433](https://pubmed.ncbi.nlm.nih.gov/41327433/). *Genome biology*. [Basic Science / Preclinical]
López CL (2025). [PMID: 40976132](https://pubmed.ncbi.nlm.nih.gov/40976132/). *Clinics (Sao Paulo, Brazil)*. [Diagnostic / Biomarker]