Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy
A hypertrophic cardiomyopathy associated that has material basis in region 7p12.1-q21 variation.
Features include always present findings: Thickened heart muscle (hypertrophic cardiomyopathy); and sometimes findings: Atrial fibrillation, Mitral valve prolapse, and Sudden death. 6 total HPO annotations.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Heart and blood vessels | 4 | Thickened heart muscle (hypertrophic cardiomyopathy), Atrial fibrillation, Thickened left heart wall (left ventricular hypertrophy) |
Biomarker and diagnostic research for hypertrophic cardiomyopathy 21 has been reported in the published literature.
Phenotype severity distribution: 1 always present feature.
No clinical trials have been registered for hypertrophic cardiomyopathy 21.
251 publications have been identified in PubMed for hypertrophic cardiomyopathy 21. Research spans Epidemiology / Natural History (23%), Basic Science / Preclinical (20%), and Review / Meta-Analysis (19%).
Research Type | Count | % of Total |
|---|---|---|
Disease patterns and progression | 57 | 23% |
Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 11:55 PM UTC
Online Mendelian Inheritance in Man
Laboratory research
50 |
20% |
Research summaries | 47 | 19% |
Testing and diagnosis research | 40 | 16% |
Clinical study results | 37 | 15% |
Patient case studies | 11 | 4% |
Other research | 6 | 2% |
New treatment approaches | 3 | 1% |
So ACF (2026). [PMID: 41577587](https://pubmed.ncbi.nlm.nih.gov/41577587/). *Heart Lung Circ*. [Epidemiology / Natural History]
Kleeberger JA (2026). [PMID: 41584504](https://pubmed.ncbi.nlm.nih.gov/41584504/). *Eur Heart J Imaging Methods Pract*. [Review / Meta-Analysis]
Indennidate C (2026). [PMID: 41636929](https://pubmed.ncbi.nlm.nih.gov/41636929/). *Curr Cardiol Rep*. [Review / Meta-Analysis]
Ioannou A (2026). [PMID: 41674454](https://pubmed.ncbi.nlm.nih.gov/41674454/). *Circ Cardiovasc Imaging*. [Diagnostic / Biomarker]
Nazarie FV (2026). [PMID: 42072833](https://pubmed.ncbi.nlm.nih.gov/42072833/). *Diagnostics (Basel)*. [Basic Science / Preclinical]
Kiselev E (2026). [PMID: 41215595](https://pubmed.ncbi.nlm.nih.gov/41215595/). *British journal of pharmacology*. [Basic Science / Preclinical]
Liu N (2026). [PMID: 40884535](https://pubmed.ncbi.nlm.nih.gov/40884535/). *J Magn Reson Imaging*. [Epidemiology / Natural History]
Nogueira-Garcia B (2026). [PMID: 41407035](https://pubmed.ncbi.nlm.nih.gov/41407035/). *J Cardiol*. [Review / Meta-Analysis]
Karadzha A (2026). [PMID: 42119720](https://pubmed.ncbi.nlm.nih.gov/42119720/). *J Thorac Cardiovasc Surg*. [Clinical Trial Publication]
Gözen Bayramoğlu G (2026). [PMID: 41660854](https://pubmed.ncbi.nlm.nih.gov/41660854/). *Pediatr Int*. [Basic Science / Preclinical]