Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy
A syndrome characterized by hypotrichosis, syndactyly, intellectual deficit and early eruption of teeth. It has been described in two patients. The mode of transmission appears to be autosomal recessive.
Estimated prevalence: <1 in 1,000,000 (VERY_RARE).
No clinical trials have been registered for hypotrichosis-intellectual disability, Lopes type.
5 publications have been identified in PubMed for hypotrichosis-intellectual disability, Lopes type. Research spans Review / Meta-Analysis (40%), Basic Science / Preclinical (40%), and Case Report / Case Series (20%).
de Avellar NBC (2026). [PMID: 39763025](https://pubmed.ncbi.nlm.nih.gov/39763025/). *Prosthet Orthot Int*. [Review / Meta-Analysis]
Melo RC (2025). [PMID: 41002725](https://pubmed.ncbi.nlm.nih.gov/41002725/). *Diseases*. [Review / Meta-Analysis]
Félix Cabral M (2025). [PMID: 41091595](https://pubmed.ncbi.nlm.nih.gov/41091595/). *Acta Med Port*. [Case Report / Case Series]
Howes OD (2025). [PMID: 41130556](https://pubmed.ncbi.nlm.nih.gov/41130556/). *Biol Psychiatry*. [Basic Science / Preclinical]
Lopes FM (2024). [PMID: 38990208](https://pubmed.ncbi.nlm.nih.gov/38990208/). *Elife*. [Basic Science / Preclinical]
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 4:48 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center