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A malignant germ cell tumor arising from the ovary. It usually affects females in their first two decades of life. It contains variable amounts of immature embryonal tissues. Based on the amount of immature neuroepithelial component, immature teratomas are graded from 1 to 3. The stage and grade of the tumor and the grade of the metastatic tumor are the important factors that predict prognosis. The use of cisplatin-based combination chemotherapy has significantly improved the survival rates of the patients.
Biomarker and diagnostic research for immature ovarian teratoma has been reported in the published literature.
Estimated prevalence: Unknown (Unknown prevalence).
1 clinical trial registered, 1 recruiting. Interventions under study include drug therapy, other interventions, procedural interventions, and biologic therapy. Pipeline includes 1 PHASE3. Research is primarily sponsored by academic and government institutions.
37 publications have been identified in PubMed for immature ovarian teratoma. Research spans Case Report / Case Series (46%), Epidemiology / Natural History (19%), and Clinical Trial Publication (16%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 17 |
Data assembled from 4 of 12 sources · Last updated Nov 5, 2026, 9:57 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
46%
Disease patterns and progression | 7 | 19% |
Clinical study results | 6 | 16% |
Laboratory research | 4 | 11% |
Other research | 1 | 3% |
Testing and diagnosis research | 1 | 3% |
Research summaries | 1 | 3% |
Simone K (2026). [PMID: 41456400](https://pubmed.ncbi.nlm.nih.gov/41456400/). *Journal of neuroimmunology*. [Case Report / Case Series]
Rogalidou M (2026). [PMID: 41562819](https://pubmed.ncbi.nlm.nih.gov/41562819/). *Reports (MDPI)*. [Epidemiology / Natural History]
Landolfo C (2026). [PMID: 41118662](https://pubmed.ncbi.nlm.nih.gov/41118662/). *Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology*. [Clinical Trial Publication]
Dick A (2026). [PMID: 41166791](https://pubmed.ncbi.nlm.nih.gov/41166791/). *European journal of obstetrics, gynecology, and reproductive biology*. [Basic Science / Preclinical]
Lin LH (2026). [PMID: 41498302](https://pubmed.ncbi.nlm.nih.gov/41498302/). *Histopathology*. [Epidemiology / Natural History]
Ahmed A (2026). [PMID: 33231995](https://pubmed.ncbi.nlm.nih.gov/33231995/). *Unknown Journal*. [Case Report / Case Series]
Zanfagnin V (2026). [PMID: 41887253](https://pubmed.ncbi.nlm.nih.gov/41887253/). *Arch Pathol Lab Med*. [Basic Science / Preclinical]
Shi Y (2026). [PMID: 42094196](https://pubmed.ncbi.nlm.nih.gov/42094196/). *Front Oncol*. [Case Report / Case Series]
Gatta G (2025). [PMID: 40180806](https://pubmed.ncbi.nlm.nih.gov/40180806/). *European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology*. [Epidemiology / Natural History]
Liang Y (2025). [PMID: 40781056](https://pubmed.ncbi.nlm.nih.gov/40781056/). *Pathology*. [Case Report / Case Series]
AI-curated news mentioning immature ovarian teratoma
Updated Sep 28, 2026
A case report details metastatic neuroblastoma originating from an ovarian immature teratoma in a 16-year-old female. This unique presentation highlights the complexities of diagnosing and treating rare pediatric cancers.
A recent study published in PubMed explores the occurrence of mucinous adenocarcinoma in mature ovarian teratomas. This research adds to the understanding of tumor behavior in rare ovarian conditions.
A recent study explores the ultrasound patterns of ovarian immature teratomas, identifying pebbled mosaic-like heterogeneous echogenicity as a significant feature. This research correlates these patterns with pathological grades, potentially aiding in diagnosis.