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ovarian yolk sac tumor - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

ovarian yolk sac tumor

MONDO:0006344

Also known as:endodermal sinus neoplasm of ovaryendodermal sinus neoplasm of the ovaryendodermal sinus tumor of ovary

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Overview

A usually rapidly growing malignant germ cell tumor arising from the ovary. It usually occurs in children and adolescents. Signs and symptoms include abdominal pain and a large abdominal or pelvic mass. The serum alpha-fetoprotein is almost always elevated preoperatively. Morphologically, there is marked heterogeneity due to numerous patterns of differentiation coexisting in the same tumor. The most common pattern is reticular.

Clinical Trials1 registered

Diagnosis

Biomarker and diagnostic research for ovarian yolk sac tumor has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

1 clinical trial registered. Interventions under study include drug therapy, other interventions, procedural interventions, and biologic therapy. Pipeline includes 1 PHASE3. Research is primarily sponsored by academic and government institutions.

19 publications have been identified in PubMed for ovarian yolk sac tumor. Research spans Case Report / Case Series (79%), Diagnostic / Biomarker (5%), and Review / Meta-Analysis (5%).

Research Type	Count	% of Total
Patient case studies	15

Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 12:03 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

Questions for Your Care Team

→Are any of the 1 active clinical trial a good fit for my situation?
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ovarian yolk sac tumor

Overview

Diagnosis

Research Landscape

Medical References

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Recent Publications