Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy
An invasive transitional cell carcinoma that arises from the urinary bladder urothelium.
Biomarker and diagnostic research for infiltrating bladder urothelial carcinoma has been reported in the published literature.
32 clinical trials registered, 12 recruiting. Interventions under study include drug therapy, other interventions, procedural interventions, and biologic therapy. Pipeline includes 1 PHASE4, 2 PHASE3, 12 PHASE2. Research is sponsored by a mix of industry and academic institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT05987241](https://clinicaltrials.gov/study/NCT05987241) |
Data assembled from 3 of 12 sources · Last updated Sep 18, 2026, 11:36 PM UTC
Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study |
PHASE2 |
National Cancer Institute (NCI) |
RECRUITING |
[NCT06809140](https://clinicaltrials.gov/study/NCT06809140) | Enfortumab Vedotin Plus Pembrolizumab With Selective Bladder Sparing for Treatment of Muscle-invasive Bladder Cancer | PHASE2 | Matthew Galsky | RECRUITING |
[NCT06396533](https://clinicaltrials.gov/study/NCT06396533) | Increasing Pre-Surgical Identification of Muscle Invasive Tumor Evaluations Prior to Planned Cystectomy (INSITE) | — | Fox Chase Cancer Center | RECRUITING |
[NCT07061964](https://clinicaltrials.gov/study/NCT07061964) | Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial | PHASE2 | National Cancer Institute (NCI) | RECRUITING |
[NCT06770582](https://clinicaltrials.gov/study/NCT06770582) | Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial | PHASE2 | National Cancer Institute (NCI) | RECRUITING |
73 publications have been identified in PubMed for infiltrating bladder urothelial carcinoma. Research spans Basic Science / Preclinical (36%), Diagnostic / Biomarker (23%), and Epidemiology / Natural History (12%).
Research Type | Count | % of Total |
|---|---|---|
Laboratory research | 26 | 36% |
Testing and diagnosis research | 17 | 23% |
Disease patterns and progression | 9 | 12% |
Research summaries | 7 | 10% |
Patient case studies | 6 | 8% |
Clinical study results | 4 | 5% |
Other research | 2 | 3% |
New treatment approaches | 2 | 3% |
Roupret M (2026). [PMID: 41110692](https://pubmed.ncbi.nlm.nih.gov/41110692/). *Ann Oncol*. [Clinical Trial Publication]
Wu DJ (2026). [PMID: 41650796](https://pubmed.ncbi.nlm.nih.gov/41650796/). *Seminars in diagnostic pathology*. [Review / Meta-Analysis]
Yan X (2026). [PMID: 41876361](https://pubmed.ncbi.nlm.nih.gov/41876361/). *Cancer Med*. [Diagnostic / Biomarker]
van Creij NCH (2026). [PMID: 41804750](https://pubmed.ncbi.nlm.nih.gov/41804750/). *Clin Transl Med*. [Basic Science / Preclinical]
Chen F (2025). [PMID: 39956899](https://pubmed.ncbi.nlm.nih.gov/39956899/). *BMC Med Genomics*. [Basic Science / Preclinical]
Johnson BA (2025). [PMID: 39971624](https://pubmed.ncbi.nlm.nih.gov/39971624/). *The journal of pathology. Clinical research*. [Basic Science / Preclinical]
Wang T (2025). [PMID: 40893939](https://pubmed.ncbi.nlm.nih.gov/40893939/). *Front Genet*. [Diagnostic / Biomarker]
Jin J (2025). [PMID: 40134825](https://pubmed.ncbi.nlm.nih.gov/40134825/). *Am J Clin Exp Immunol*. [Diagnostic / Biomarker]
Relvas-Santos M (2025). [PMID: 40430030](https://pubmed.ncbi.nlm.nih.gov/40430030/). *Int J Mol Sci*. [Basic Science / Preclinical]
Cui J (2025). [PMID: 40100478](https://pubmed.ncbi.nlm.nih.gov/40100478/). *Discov Oncol*. [Basic Science / Preclinical]