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intellectual disability, X-linked 2 (MRX2) - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

intellectual disability, X-linked 2

MONDO:0010322

Also known as:MRX2mental retardation, X-linked 2

Overview

GeneticsX-linked

Clinical Presentation

Built from Human Phenotype Ontology (HPO) phenotype annotations and GeneReviews clinical descriptions. Features represent findings documented across known cases — not an exhaustive list of possible symptoms.

Features include: Square face, Short stature, Poor fine motor coordination, and Macroorchidism and 3 more.

Organ System	Phenotype Count	Example Features
Head and neck	3	Square face, Relative macrocephaly, High palate
Brain and nerves

Diagnosis

Biomarker and diagnostic research for intellectual disability, X-linked 2 has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for intellectual disability, X-linked 2.

202 publications have been identified in PubMed for intellectual disability, X-linked 2. Kisho has analyzed 86 by research type. Research spans Basic Science / Preclinical (30%), Review / Meta-Analysis (22%), and Case Report / Case Series (12%).

Research Type	Count	% of Total
Laboratory research	26	30%

Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 7:49 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

OMIM

Online Mendelian Inheritance in Man

OMIM:300428

GARD

Genetic and Rare Diseases Info Center

GARD:22675

Questions for Your Care Team

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Kisho

intellectual disability, X-linked 2

Overview

Clinical Presentation

Diagnosis

Research Landscape

Medical References

External Resources

OMIM

GARD

Questions for Your Care Team

Questions for Your Care Team

Explore clinical features

Recent Publications

intellectual disability, X-linked 2

Overview

Clinical Presentation

Diagnosis

Research Landscape

Medical References

External Resources

OMIM

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Explore clinical features

Recent Publications