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Interventricular septum aneurysm is a rare, non-syndromic, congenital heart malformation characterized by the presence of a congenital aneurysm of the membranous portion of the interventricular septum. Patients may be asymptomatic or may present with ventricular or supraventricular tachycardia, fatigue, exertional dyspnea, palpitations, and cardiac murmur. Ventricular septal defects and conduction defects, such as first-degree atrio-ventricular block or incomplete right bundle branch block, may also be also associated.
Features include: Vascular dilatation and Abnormal ventricular septum morphology.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Heart and blood vessels | 1 | Abnormal ventricular septum morphology |
Biomarker and diagnostic research for interventricular septum aneurysm has been reported in the published literature.
No clinical trials have been registered for interventricular septum aneurysm.
8 publications have been identified in PubMed for interventricular septum aneurysm. Research spans Case Report / Case Series (88%) and Diagnostic / Biomarker (13%).
Ku L (2025). [PMID: 40461027](https://pubmed.ncbi.nlm.nih.gov/40461027/). *Eur Heart J Cardiovasc Imaging*. [Case Report / Case Series]
Erdem S (2025). [PMID: 40384730](https://pubmed.ncbi.nlm.nih.gov/40384730/). *Methodist Debakey Cardiovasc J*. [Case Report / Case Series]
Morais H (2025). [PMID: 40037581](https://pubmed.ncbi.nlm.nih.gov/40037581/). *Eur Heart J Cardiovasc Imaging*. [Case Report / Case Series]
Kumar SS (2025). [PMID: 40667451](https://pubmed.ncbi.nlm.nih.gov/40667451/). *Eur Heart J Case Rep*. [Case Report / Case Series]
Zhou T (2024). [PMID: 39286729](https://pubmed.ncbi.nlm.nih.gov/39286729/). *Eur Heart J Case Rep*. [Case Report / Case Series]
Data assembled from 5 of 12 sources · Last updated Sep 19, 2026, 8:50 AM UTC
Online Mendelian Inheritance in Man
European rare disease database
Genetic and Rare Diseases Info Center
He J (2024). [PMID: 38923632](https://pubmed.ncbi.nlm.nih.gov/38923632/). *Echocardiography*. [Case Report / Case Series]
Cherkani Hassani Y (2024). [PMID: 38963078](https://pubmed.ncbi.nlm.nih.gov/38963078/). *Acta Cardiol*. [Diagnostic / Biomarker]
AI-curated news mentioning interventricular septum aneurysm
Updated Mar 19, 2026
A recent study published in PubMed discusses thigh compartment syndrome as a complication following physician-modified fenestrated endograft aneurysm repair. This research highlights the need for awareness of potential post-operative complications in vascular surgeries.
A recent case report details an enormous aneurysm of the deep femoral artery, contributing to the understanding of vascular anomalies. This case highlights the complexities involved in diagnosing and managing such rare vascular conditions.