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Congenital alacrima is characterized by deficient lacrimation (ranging from a complete absence of tears to hyposecretion of tears) that is present from birth.
Estimated prevalence: Unknown (Unknown prevalence).
No clinical trials have been registered for isolated congenital alacrima.
3 publications have been identified in PubMed for isolated congenital alacrima. Kisho has analyzed 2 by research type. Research spans Review / Meta-Analysis (50%) and Case Report / Case Series (50%).
Jarvis JHM (2026). [PMID: 41689776](https://pubmed.ncbi.nlm.nih.gov/41689776/). *Vet Radiol Ultrasound*. [Case Report / Case Series]
Cetin SK (2025). [PMID: 40353455](https://pubmed.ncbi.nlm.nih.gov/40353455/). *Turk Arch Pediatr*. [Review / Meta-Analysis]
Data assembled from 3 of 12 sources · Last updated Sep 18, 2026, 5:29 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center