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joint laxity, familial - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

joint laxity, familial

MONDO:0007842

Also known as:EDS XIEhlers-Danlos syndrome type 11, formerlyJoint instability syndrome

Overview

A type of Ehlers-Danlos syndrome characterized by generalized joint hypermobility often complicated by dislocation of major joints, particularly the shoulder but in some cases the kneecap. Congenital hip dislocation has also been frequently reported. The syndrome has been described in several families. It is transmitted as an autosomal dominant trait, with high penetrance.

ResearchLimited published research (9 articles)

Prognosis

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for joint laxity, familial.

9 publications have been identified in PubMed for joint laxity, familial. Research spans Epidemiology / Natural History (44%), Case Report / Case Series (22%), and Review / Meta-Analysis (11%).

Recent Publications

Williams CM (2026). [PMID: 41990439](https://pubmed.ncbi.nlm.nih.gov/41990439/). *J Psychosom Res*. [Epidemiology / Natural History]
Tale E (2026). [PMID: 40530951](https://pubmed.ncbi.nlm.nih.gov/40530951/). *Journal of osteopathic medicine*. [Clinical Trial Publication]
Kampoureli CN (2026). [PMID: 39895195](https://pubmed.ncbi.nlm.nih.gov/39895195/). *The British journal of psychiatry : the journal of mental science*. [Basic Science / Preclinical]
Bruessel P (2026). [PMID: 41924132](https://pubmed.ncbi.nlm.nih.gov/41924132/). *Vasc Health Risk Manag*. [Review / Meta-Analysis]
Çevirici T (2026). [PMID: 42098330](https://pubmed.ncbi.nlm.nih.gov/42098330/). *Eur J Pediatr*. [Epidemiology / Natural History]

Data assembled from 4 of 12 sources · Last updated Sep 18, 2026, 8:40 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

OMIM

Online Mendelian Inheritance in Man

OMIM:147900

Orphanet

European rare disease database

Orphanet:2295

GARD

Genetic and Rare Diseases Info Center

GARD:3054

Questions for Your Care Team

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joint laxity, familial

Overview

Prognosis

Research Landscape

Recent Publications

Medical References

External Resources

OMIM

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team