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juvenile temporal arteritis (JTA) - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

juvenile temporal arteritis

MONDO:0016848

Also known as:JTAnon-giant cell granulomatous temporal arteritis with eosinophiliaJGCA

Overview

Juvenile temporal arteritis is a rare form of vasculitis, a group of conditions that cause inflammation of the blood vessels. Unlike the classic form of temporal arteritis, this condition is generally diagnosed in late childhood or early adulthood and only affects the temporal arteries (located at the lower sides of the skull, directly underneath the temple). Affected people often have no signs or symptoms aside from a painless nodule or lump in the temporal region. The exact underlying cause of the condition is unknown. It generally occurs sporadically in people with no family history of the condition. Juvenile temporal arteritis is often treated with surgical excision and rarely recurs.

Clinical Presentation

Built from Human Phenotype Ontology (HPO) phenotype annotations and GeneReviews clinical descriptions. Features represent findings documented across known cases — not an exhaustive list of possible symptoms.

Features include common findings: Elevated white blood cell count (increased total leukocyte count), Headache, and Skin nodule; and sometimes findings: Conjunctivitis, Increased total eosinophil count, and Allergic rhinitis.

Organ System	Phenotype Count	Example Features
Blood and immune system	1	Elevated white blood cell count (increased total leukocyte count)

Diagnosis

Biomarker and diagnostic research for juvenile temporal arteritis has been reported in the published literature.

Prognosis

Phenotype severity distribution: 3 common features.

Estimated prevalence: <1 in 1,000,000 (VERY_RARE).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for juvenile temporal arteritis.

130 publications have been identified in PubMed for juvenile temporal arteritis. Research spans Review / Meta-Analysis (48%), Epidemiology / Natural History (17%), and Diagnostic / Biomarker (11%).

Research Type	Count	% of Total
Research summaries	63	48%

Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 1:58 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:26137

GARD

Genetic and Rare Diseases Info Center

GARD:3068

Questions for Your Care Team

→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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juvenile temporal arteritis

Overview

Clinical Presentation

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Questions for Your Care Team

Questions for Your Care Team

Explore clinical features

Recent Publications

juvenile temporal arteritis

Overview

Clinical Presentation

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Explore clinical features

Recent Publications