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A pneumonia caused by Legionella pneumophila and other Legionella species, which is characterized by fever, cough, progressive respiratory distress, and which is often accompanied by extrapulmonary manifestations.
Biomarker and diagnostic research for Legionnaires' disease has been reported in the published literature.
1 FDA-approved treatment is available for Legionnaires' disease, including ERYTHROMYCIN (ERYTHROMYCIN, approved 1981).
Brand Name | Generic Name | Mechanism | Approved | Market Status |
|---|---|---|---|---|
1 clinical trial registered. Interventions under study include medical devices. Pipeline includes 1 NA. Research is primarily sponsored by academic and government institutions.
309 publications have been identified in PubMed for Legionnaires' disease. Kisho has analyzed 113 by research type. Research spans Basic Science / Preclinical (31%), Epidemiology / Natural History (26%), and Case Report / Case Series (16%).
Research Type | Count | % of Total |
|---|---|---|
Laboratory research | 35 |
Data assembled from 5 of 12 sources · Last updated Sep 20, 2026, 5:14 AM UTC
European rare disease database
Common questions about Legionnaires' disease
ERYTHROMYCIN |
— |
1981 |
Available |
Gene therapy approaches for Legionnaires' disease have been reported in the published literature.
1 trial found
Disease patterns and progression | 29 | 26% |
Patient case studies | 18 | 16% |
Research summaries | 12 | 11% |
Testing and diagnosis research | 9 | 8% |
Other research | 5 | 4% |
Clinical study results | 3 | 3% |
New treatment approaches | 2 | 2% |
Farzam K (2026). [PMID: 30335282](https://pubmed.ncbi.nlm.nih.gov/30335282/). *Unknown Journal*. [Basic Science / Preclinical]
Shin CJ (2026). [PMID: 41798756](https://pubmed.ncbi.nlm.nih.gov/41798756/). *Front Cell Infect Microbiol*. [Review / Meta-Analysis]
Rijal R (2026). [PMID: 41334932](https://pubmed.ncbi.nlm.nih.gov/41334932/). *Microbiol Spectr*. [Epidemiology / Natural History]
Bledsoe ME (2026). [PMID: 41612569](https://pubmed.ncbi.nlm.nih.gov/41612569/). *Emerg Infect Dis*. [Epidemiology / Natural History]
Arqué E (2026). [PMID: 41534336](https://pubmed.ncbi.nlm.nih.gov/41534336/). *Water Res*. [Epidemiology / Natural History]
Vișan CA (2026). [PMID: 42075329](https://pubmed.ncbi.nlm.nih.gov/42075329/). *Microorganisms*. [Basic Science / Preclinical]
Paglione F (2026). [PMID: 41753772](https://pubmed.ncbi.nlm.nih.gov/41753772/). *Microorganisms*. [Case Report / Case Series]
Cheng R (2026). [PMID: 41684123](https://pubmed.ncbi.nlm.nih.gov/41684123/). *Ann Med*. [Diagnostic / Biomarker]
Robesyn E (2026). [PMID: 41996520](https://pubmed.ncbi.nlm.nih.gov/41996520/). *PLoS One*. [Diagnostic / Biomarker]
Ma J (2026). [PMID: 41983107](https://pubmed.ncbi.nlm.nih.gov/41983107/). *Infect Drug Resist*. [Review / Meta-Analysis]
AI-curated news mentioning Legionnaires' disease
Updated Feb 7, 2026
A rare case report highlights an unexpected diagnosis of Legionnaires' disease in a patient initially thought to have bronchopneumonia, which progressed to sepsis. This case underscores the importance of considering rare diseases in differential diagnoses.
The CDC released a transcript from a telebriefing on Legionnaires' disease, providing insights into public health responses and awareness efforts. This document serves as a resource for understanding the ongoing challenges related to this disease.
A new CDC report highlights the significant risk of Legionnaires' disease in healthcare facilities, noting a mortality rate of 25% among affected patients. This underscores the need for increased awareness and preventive measures in healthcare settings.
A CDC analysis reveals that 76% of 21 U.S. jurisdictions reported health care-associated cases of Legionnaires' disease, highlighting the risks patients face in health care facilities. This finding underscores the need for improved infection control measures.