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Pontiac fever (PF) is a mild form of legionellosis manifesting with flu-like symptoms such as nausea, myalgia, fever, cough and headache but without pneumonia.
Biomarker and diagnostic research for Pontiac fever has been reported in the published literature.
Estimated prevalence: Unknown (Unknown prevalence).
No clinical trials have been registered for Pontiac fever.
10 publications have been identified in PubMed for Pontiac fever. Research spans Case Report / Case Series (33%), Basic Science / Preclinical (33%), and Epidemiology / Natural History (22%).
Tang L (2026). [PMID: 41621271](https://pubmed.ncbi.nlm.nih.gov/41621271/). *Water research*. [Epidemiology / Natural History]
Khomynets R (2026). [PMID: 41835684](https://pubmed.ncbi.nlm.nih.gov/41835684/). *Cureus*. [Case Report / Case Series]
Rice M (2025). [PMID: 40585611](https://pubmed.ncbi.nlm.nih.gov/40585611/). *Cureus*. [Case Report / Case Series]
Zhang C (2025). [PMID: 40463979](https://pubmed.ncbi.nlm.nih.gov/40463979/). *Frontiers in medicine*. [Case Report / Case Series]
Hem S (2025). [PMID: 40742217](https://pubmed.ncbi.nlm.nih.gov/40742217/). *Journal of water and health*. [Basic Science / Preclinical]
Bertolino G (2025). [PMID: 37777698](https://pubmed.ncbi.nlm.nih.gov/37777698/). *Advances in experimental medicine and biology*. [Diagnostic / Biomarker]
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 8:40 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Common questions about Pontiac fever
Angert DM (2025). [PMID: 40816012](https://pubmed.ncbi.nlm.nih.gov/40816012/). *Water research*. [Basic Science / Preclinical]
Wade TJ (2024). [PMID: 39417401](https://pubmed.ncbi.nlm.nih.gov/39417401/). *Epidemiology and infection*. [Epidemiology / Natural History]
Carr SM (2024). [PMID: 39065134](https://pubmed.ncbi.nlm.nih.gov/39065134/). *Microorganisms*. [Basic Science / Preclinical]