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Biomarker and diagnostic research for Leigh syndrome with cardiomyopathy has been reported in the published literature.
No clinical trials have been registered for Leigh syndrome with cardiomyopathy.
40 publications have been identified in PubMed for Leigh syndrome with cardiomyopathy. Research spans Basic Science / Preclinical (38%), Review / Meta-Analysis (28%), and Case Report / Case Series (20%).
Research Type | Count | % of Total |
|---|---|---|
Laboratory research | 15 | 38% |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 11:58 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Research summaries
11 |
28% |
Patient case studies | 8 | 20% |
Disease patterns and progression | 3 | 8% |
Testing and diagnosis research | 1 | 3% |
Clinical study results | 1 | 3% |
New treatment approaches | 1 | 3% |
Lan SC (2026). [PMID: 42091683](https://pubmed.ncbi.nlm.nih.gov/42091683/). *Neurol Sci*. [Case Report / Case Series]
Terburgh K (2026). [PMID: 41532297](https://pubmed.ncbi.nlm.nih.gov/41532297/). *J Inherit Metab Dis*. [Basic Science / Preclinical]
Ugarteburu O (2026). [PMID: 41203052](https://pubmed.ncbi.nlm.nih.gov/41203052/). *Mitochondrion*. [Case Report / Case Series]
Tan NB (2026). [PMID: 41916321](https://pubmed.ncbi.nlm.nih.gov/41916321/). *Am J Hum Genet*. [Basic Science / Preclinical]
Khumalo SG (2026). [PMID: 41506052](https://pubmed.ncbi.nlm.nih.gov/41506052/). *Mol Genet Metab*. [Basic Science / Preclinical]
Banerjee S (2026). [PMID: 41850596](https://pubmed.ncbi.nlm.nih.gov/41850596/). *Mitochondrion*. [Epidemiology / Natural History]
Selamioglu A (2026). [PMID: 40944834](https://pubmed.ncbi.nlm.nih.gov/40944834/). *Am J Med Genet A*. [Review / Meta-Analysis]
Menacho C (2026). [PMID: 42009687](https://pubmed.ncbi.nlm.nih.gov/42009687/). *Nat Commun*. [Diagnostic / Biomarker]
Baris S (2026). [PMID: 41683799](https://pubmed.ncbi.nlm.nih.gov/41683799/). *Int J Mol Sci*. [Case Report / Case Series]
Marquez J (2025). [PMID: 39967265](https://pubmed.ncbi.nlm.nih.gov/39967265/). *HGG Adv*. [Basic Science / Preclinical]
AI-curated news mentioning Leigh syndrome with cardiomyopathy
Updated Aug 26, 2026
An interim analysis from a multi-site study provides insights into the clinical presentation and progression of Leigh syndrome spectrum disorders. This research aims to enhance understanding of these rare diseases and inform future therapeutic strategies.
A recent study highlights β-ureidopropionase deficiency presenting symptoms similar to Leigh syndrome, alongside methylmalonic aciduria. This discovery may aid in better diagnosis and understanding of these rare metabolic disorders.