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leiomyosarcoma of the cervix uteri - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

leiomyosarcoma of the cervix uteri

MONDO:0016283

Also known as:cervical leiomyosarcomaleiomyosarcoma of uterine cervixuterine cervix leiomyosarcoma

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Overview

Leiomyosarcoma of the cervix uteri is a rare, malignant mesenchymal tumor of smooth muscle origin, macroscopically appearing as a large, poorly circumscribed mass, often protruding from the cervical canal or expanding it circumferentially. The most common presenting symptoms are vaginal discharge or bleeding, pain in the lower abdomen and a bulky cervical mass. There is a reported tendency to metastatsize hematogenously, especially to the lungs, peritoneum, bones and the liver.

Clinical Trials1 registered · 1 recruiting

ResearchLimited published research (8 articles)

Diagnosis

Biomarker and diagnostic research for leiomyosarcoma of the cervix uteri has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

1 clinical trial registered, 1 recruiting. Interventions under study include other interventions. Research is primarily sponsored by academic and government institutions.

8 publications have been identified in PubMed for leiomyosarcoma of the cervix uteri. Research spans Case Report / Case Series (38%), Diagnostic / Biomarker (25%), and Other (13%).

Recent Publications

Bottazzi S (2026). [PMID: 40704674](https://pubmed.ncbi.nlm.nih.gov/40704674/). *Br J Radiol*. [Review / Meta-Analysis]
Walpole S (2026). [PMID: 41277477](https://pubmed.ncbi.nlm.nih.gov/41277477/). *Clin Genet*. [Case Report / Case Series]
Mathur P (2025). [PMID: 41474561](https://pubmed.ncbi.nlm.nih.gov/41474561/). *J Cancer Res Ther*. [Diagnostic / Biomarker]
Prabhat P (2025). [PMID: 40861708](https://pubmed.ncbi.nlm.nih.gov/40861708/). *Cureus*. [Case Report / Case Series]
De S (2025). [PMID: 41341478](https://pubmed.ncbi.nlm.nih.gov/41341478/). *J Cytol*. [Diagnostic / Biomarker]

Data assembled from 4 of 12 sources · Last updated Sep 20, 2026, 5:52 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:213807

GARD

Genetic and Rare Diseases Info Center

GARD:20495

Questions for Your Care Team

→Are any of the 1 active clinical trial a good fit for my situation?
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leiomyosarcoma of the cervix uteri

Overview

Diagnosis

Research Landscape

Recent Publications

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team