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Lemierre syndrome is a rare, potentially lethal, oropharyngeal infectious disease occurring in immunocompetent adolescents and young adults that is mainly due to Fusobacterium necrophorum and that is characterized by septic thrombophlebitis of the internal jugular vein that leads to septic, usually pulmonary, embolism, associated with ENT (ear, nose, and throat) infection that manifests with fever, neck pain, and tonsillopharyngitis.
Biomarker and diagnostic research for Lemierre syndrome has been reported in the published literature.
Estimated prevalence: Unknown (Unknown prevalence).
No clinical trials have been registered for Lemierre syndrome.
140 publications have been identified in PubMed for Lemierre syndrome. Research spans Case Report / Case Series (76%), Review / Meta-Analysis (11%), and Epidemiology / Natural History (6%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 107 | 76% |
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 11:11 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Common questions about Lemierre syndrome
15 |
11% |
Disease patterns and progression | 8 | 6% |
Laboratory research | 4 | 3% |
Other research | 3 | 2% |
Testing and diagnosis research | 1 | 1% |
Clinical study results | 1 | 1% |
New treatment approaches | 1 | 1% |
He M (2026). [PMID: 41607010](https://pubmed.ncbi.nlm.nih.gov/41607010/). *J Clin Ultrasound*. [Case Report / Case Series]
Moffett KS (2026). [PMID: 40966739](https://pubmed.ncbi.nlm.nih.gov/40966739/). *Pediatr Infect Dis J*. [Case Report / Case Series]
Mastroianni A (2026). [PMID: 41946445](https://pubmed.ncbi.nlm.nih.gov/41946445/). *Int J Infect Dis*. [Case Report / Case Series]
Dingle E (2026). [PMID: 41342464](https://pubmed.ncbi.nlm.nih.gov/41342464/). *Clin Pediatr (Phila)*. [Case Report / Case Series]
Yang X (2026). [PMID: 41535786](https://pubmed.ncbi.nlm.nih.gov/41535786/). *BMC Infect Dis*. [Case Report / Case Series]
Cheng BYC (2026). [PMID: 42009365](https://pubmed.ncbi.nlm.nih.gov/42009365/). *CMAJ*. [Review / Meta-Analysis]
Aytaç A (2026). [PMID: 41982742](https://pubmed.ncbi.nlm.nih.gov/41982742/). *BJR Case Rep*. [Case Report / Case Series]
Lesage L (2026). [PMID: 41511544](https://pubmed.ncbi.nlm.nih.gov/41511544/). *Pediatr Radiol*. [Case Report / Case Series]
Yale SH (2026). [PMID: 42006537](https://pubmed.ncbi.nlm.nih.gov/42006537/). *Clin Case Rep*. [Other]
Zeltina E (2026). [PMID: 42014164](https://pubmed.ncbi.nlm.nih.gov/42014164/). *BMJ Case Rep*. [Case Report / Case Series]
AI-curated news mentioning Lemierre syndrome
Updated Aug 7, 2026
A case report highlights an atypical presentation of Lemierre syndrome in a child with nephrotic syndrome, contributing to the understanding of this rare condition. The literature review provides insights into the clinical features and management strategies.