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A squamous cell carcinoma arising from the lip or the oral cavity. The oral cavity squamous cell carcinoma usually arises from the buccal mucosa, tongue, or gums. It occurs predominantly in adults who use tobacco and alcohol and has a tendency to metastasize early to lymph nodes.
Biomarker and diagnostic research for lip and oral cavity squamous cell carcinoma has been reported in the published literature.
3 clinical trials registered, 1 recruiting. Interventions under study include drug therapy, other interventions, procedural interventions, and biologic therapy. Pipeline includes 1 PHASE3, 2 PHASE2. Research is primarily sponsored by academic and government institutions.
144 publications have been identified in PubMed for lip and oral cavity squamous cell carcinoma. Research spans Case Report / Case Series (24%), Epidemiology / Natural History (22%), and Clinical Trial Publication (14%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 35 |
Data assembled from 4 of 12 sources · Last updated Sep 20, 2026, 4:51 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
24% |
Disease patterns and progression | 31 | 22% |
Clinical study results | 20 | 14% |
Laboratory research | 20 | 14% |
Research summaries | 18 | 13% |
Testing and diagnosis research | 17 | 12% |
New treatment approaches | 3 | 2% |
Shetty C (2026). [PMID: 42225515](https://pubmed.ncbi.nlm.nih.gov/42225515/). *Oral Maxillofac Surg Clin North Am*. [Review / Meta-Analysis]
Koyama S (2026). [PMID: 41958625](https://pubmed.ncbi.nlm.nih.gov/41958625/). *JMA J*. [Epidemiology / Natural History]
Hamdi M (2026). [PMID: 41837102](https://pubmed.ncbi.nlm.nih.gov/41837102/). *Int J Surg Case Rep*. [Case Report / Case Series]
Şengüm DN (2026). [PMID: 42099139](https://pubmed.ncbi.nlm.nih.gov/42099139/). *Curr Med Chem*. [Gene Therapy / Novel Therapeutics]
Reis IA (2026). [PMID: 41420349](https://pubmed.ncbi.nlm.nih.gov/41420349/). *J Dtsch Dermatol Ges*. [Review / Meta-Analysis]
Deng M (2026). [PMID: 40982969](https://pubmed.ncbi.nlm.nih.gov/40982969/). *J Craniofac Surg*. [Epidemiology / Natural History]
Menna-Barreto CL (2026). [PMID: 41086275](https://pubmed.ncbi.nlm.nih.gov/41086275/). *Med Oral Patol Oral Cir Bucal*. [Review / Meta-Analysis]
Nasiek A (2026). [PMID: 42055785](https://pubmed.ncbi.nlm.nih.gov/42055785/). *Cancer Rep (Hoboken)*. [Case Report / Case Series]
Veiga P (2026). [PMID: 41892357](https://pubmed.ncbi.nlm.nih.gov/41892357/). *Cells*. [Diagnostic / Biomarker]
Dantas AN (2026). [PMID: 41726016](https://pubmed.ncbi.nlm.nih.gov/41726016/). *Indian J Surg Oncol*. [Basic Science / Preclinical]