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Localized Castleman disease (LCD) is the most common form of Castleman disease (CD) and it is usually asymptomatic or it may present with enlarged lymph nodes. LCD may be cured by surgical resection.
Biomarker and diagnostic research for localized Castleman disease has been reported in the published literature.
Estimated prevalence: Unknown (Unknown prevalence).
1 clinical trial registered. Interventions under study include drug therapy. Pipeline includes 1 PHASE2. Research is primarily sponsored by academic and government institutions.
111 publications have been identified in PubMed for localized Castleman disease. Research spans Case Report / Case Series (66%), Review / Meta-Analysis (16%), and Epidemiology / Natural History (9%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 73 | 66% |
Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 4:09 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Research summaries |
18 |
16% |
Disease patterns and progression | 10 | 9% |
Other research | 4 | 4% |
Laboratory research | 3 | 3% |
Testing and diagnosis research | 2 | 2% |
Clinical study results | 1 | 1% |
Alqaidy D (2026). [PMID: 41483625](https://pubmed.ncbi.nlm.nih.gov/41483625/). *Ann Diagn Pathol*. [Review / Meta-Analysis]
Laczko D (2026). [PMID: 41802815](https://pubmed.ncbi.nlm.nih.gov/41802815/). *Am J Clin Pathol*. [Review / Meta-Analysis]
Zhang L (2026). [PMID: 41952675](https://pubmed.ncbi.nlm.nih.gov/41952675/). *Frontiers in oncology*. [Case Report / Case Series]
Ozay M (2026). [PMID: 41555770](https://pubmed.ncbi.nlm.nih.gov/41555770/). *Pediatr Blood Cancer*. [Other]
Shyamsundar S (2026). [PMID: 41836733](https://pubmed.ncbi.nlm.nih.gov/41836733/). *Curr Probl Cancer Case Rep*. [Case Report / Case Series]
Vavrukh P (2026). [PMID: 41020794](https://pubmed.ncbi.nlm.nih.gov/41020794/). *Am J Dermatopathol*. [Case Report / Case Series]
Yang H (2026). [PMID: 42029937](https://pubmed.ncbi.nlm.nih.gov/42029937/). *J Cancer Res Clin Oncol*. [Case Report / Case Series]
Eng TY (2026). [PMID: 41391901](https://pubmed.ncbi.nlm.nih.gov/41391901/). *Seminars in radiation oncology*. [Review / Meta-Analysis]
Shen J (2026). [PMID: 41658580](https://pubmed.ncbi.nlm.nih.gov/41658580/). *Front Med (Lausanne)*. [Review / Meta-Analysis]
Harsha Sai J (2026). [PMID: 42037880](https://pubmed.ncbi.nlm.nih.gov/42037880/). *Cureus*. [Review / Meta-Analysis]
AI-curated news mentioning localized Castleman disease
Updated Aug 13, 2026
A recent case report details unicentric Castleman disease affecting the submandibular gland, contributing to the understanding of this rare condition. This case adds to the clinical knowledge surrounding the presentation and management of unicentric Castleman disease.