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mal de Debarquement (MDD) - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

mal de Debarquement

MONDO:0016217

Also known as:MDDMdDSdisembarkment syndrome

Overview

Mal de debarquement (MdD) is a rare otorhinolaryngological disease characterized by a persistent sensation of motion such as rocking, swaying, tumbling and/or bobbing following a period of exposure to passive movement, usually an ocean cruise or other types of water, train, automobile or air travel and less commonly other movements (like sleeping on a waterbed). Onset may be spontaneous in some patients. Manifestations begin shortly after the stimulus, persist for 6 months to years and may be associated with anxiety, fatigue and impaired cognition. Symptoms are often accentuated when in an enclosed space or when attempting to be motionless (sitting, lying down or standing in a stationary position) and are relieved when in passive motion such as in a moving car, airplane or train.

Patient Orgs2 organizations · MdDS Foundation (Mal de Débarquement Syndrome), Mal de Débarquement Syndrome Foundation

Prognosis

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for mal de Debarquement.

21 publications have been identified in PubMed for mal de Debarquement. Research spans Review / Meta-Analysis (29%), Case Report / Case Series (19%), and Clinical Trial Publication (14%).

Research Type	Count	% of Total
Research summaries	6	29%

Data assembled from 3 of 12 sources · Last updated Sep 18, 2026, 9:26 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Patient Support

Patient Advocacy Groups

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MdDS Foundation (Mal de Débarquement Syndrome)Primary Focus

USWebsite ↗

Mal de Débarquement Syndrome FoundationPrimary Focus

USWebsite ↗

Patient Advocacy Groups (PAGs) provide support, resources, and community for patients and caregivers.

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Medical References

External Resources

Orphanet

European rare disease database

Orphanet:210272

GARD

Genetic and Rare Diseases Info Center

GARD:6959

Questions for Your Care Team

→Are there specialists or centers of excellence for this condition in my area?
→How can I connect with MdDS Foundation (Mal de Débarquement Syndrome) and other patient organizations for support?

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mal de Debarquement

Overview

Prognosis

Research Landscape

Patient Support

Patient Advocacy Groups

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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