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malignancy in giant cell tumor of bone - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

malignancy in giant cell tumor of bone

MONDO:0006287

Also known as:Dedifferentiated giant cell tumorDedifferentiated giant cell tumourOSTEOCLASTOMA, malignant

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Overview

A malignant tumor that arises from the bone. It is characterized by the presence of an area of high grade sarcoma in an otherwise typical giant cell tumor (primary malignancy in giant cell tumor), or the presence of sarcoma in which the pre-existing giant cell tumor may or may not be apparent (secondary malignancy in giant cell tumor).

Clinical Trials1 registered

Diagnosis

Biomarker and diagnostic research for malignancy in giant cell tumor of bone has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

1 clinical trial registered. Interventions under study include drug therapy, other interventions, and biologic therapy. Pipeline includes 1 PHASE2. Research is primarily sponsored by academic and government institutions.

162 publications have been identified in PubMed for malignancy in giant cell tumor of bone. Research spans Review / Meta-Analysis (34%), Case Report / Case Series (23%), and Epidemiology / Natural History (14%).

Research Type	Count	% of Total
Research summaries	55

Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 5:51 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

Questions for Your Care Team

→Are any of the 1 active clinical trial a good fit for my situation?
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malignancy in giant cell tumor of bone

Overview

Diagnosis

Research Landscape

Medical References

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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