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mediastinum seminoma - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

mediastinum seminoma

MONDO:0003826

Also known as:mediastinal seminomaseminoma of mediastinumseminoma of the mediastinum

Overview

An extragonadal malignant germ cell tumor that arises from the mediastinum. It is characterized by the presence of uniform cells with clear or eosinophilic cytoplasm, round nucleus with one or more nucleoli, and distinct cellular borders. It usually arises from the anterior mediastinum. It may present with respiratory distress, chest pain, or superior vena cava syndrome or it may be asymptomatic, with the tumor detected on routine chest x-ray. The prognosis of mediastinal pure seminomas is favorable compared to the mediastinal non-seminomatous malignant germ cell tumors.

Diagnosis

Biomarker and diagnostic research for mediastinum seminoma has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for mediastinum seminoma.

41 publications have been identified in PubMed for mediastinum seminoma. Research spans Case Report / Case Series (44%), Review / Meta-Analysis (20%), and Epidemiology / Natural History (17%).

Research Type	Count	% of Total
Patient case studies	18	44%

Data assembled from 2 of 12 sources · Last updated Sep 18, 2026, 7:27 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

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mediastinum seminoma

Overview

Diagnosis

Research Landscape

Medical References

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Questions for Your Care Team

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