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mediastinal yolk sac tumor - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

mediastinal yolk sac tumor

MONDO:0023726

Also known as:endodermal sinus neoplasm of mediastinumendodermal sinus neoplasm of the mediastinumendodermal sinus tumor of mediastinum

Overview

An extragonadal non-seminomatous malignant germ cell tumor that arises from the mediastinum. It is characterized by the presence of small pale cells with small amount of cytoplasm and round to oval nuclei with small nucleoli forming a variety of patterns, including microcystic, macrocystic, pseudopapillary, myxomatous, hepatoid, polyvesicular vitelline, and solid. It manifests with respiratory distress, thoracic pain, fever, and superior vena cava syndrome.

Diagnosis

Biomarker and diagnostic research for mediastinal yolk sac tumor has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for mediastinal yolk sac tumor.

12 publications have been identified in PubMed for mediastinal yolk sac tumor. Research spans Case Report / Case Series (58%), Basic Science / Preclinical (17%), and Other (8%).

Research Type	Count	% of Total
Patient case studies	7	58%

Data assembled from 2 of 12 sources · Last updated Sep 19, 2026, 9:41 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

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mediastinal yolk sac tumor

Overview

Diagnosis

Research Landscape

Medical References

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Questions for Your Care Team

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